Proton magnetic resonance spectroscopy findings of hemangioblastoma |
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| Authors: | Tomonori Isobe Tetsuya Yamamoto Hiroyoshi Akutsu Izumi Anno Masanari Shiigai Alexander Zaboronok Tomohiko Masumoto Shingo Takano Akira Matsumura |
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| Affiliation: | 1.Graduate School of Comprehensive Human Sciences,University of Tsukuba,Tsukuba,Japan;2.Department of Neurosurgery, Graduate School of Comprehensive Human Sciences,University of Tsukuba,Tsukuba,Japan;3.Department of Radiological Sciences,Ibaraki Prefectural University of Health Sciences,Ibaraki,Japan;4.Department of Radiology, Graduate School of Comprehensive Human Sciences,University of Tsukuba,Tsukuba,Japan |
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| Abstract: | We report a case of proton magnetic resonance spectroscopy (MRS) of hemangioblastoma in a 56-yearold man with a history of
hyperlipidemia who was suffering from an equilibrium disorder. Proton MRS revealed a high mobile lipids (Lip) peak between
0.9 and 1.4 ppm, which was compatible with histologically proven lipids in the tumor. No lactate peak was recognized. The
creatine/phosphocreatine peak was low. Choline-containing compounds were increased. The N-acetylaspartate peak was absent, which indicated that the tumor is of nonneurogenic origin. Combined with the absence of
the necrotic component on magnetic resonance imaging, this Lip peak on proton MRS could be the characteristic pattern of hemangioblastoma.
These unique results of proton MRS can play an important role in the differential diagnosis of intracranial hemangioblastoma.
However, further investigations are required to establish the typical characteristics of proton MRS of hemangioblastoma. |
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