颅内原发性中枢神经系统淋巴瘤的MRI表现

目的研究颅内原发性中枢神经系统淋巴瘤（PCNSL）的MR／表现特点。方法回顾性分析8例经手术病理证实的原发性中枢神经系统淋巴瘤的MR／表现。结果8例均为弥漫大B细胞型非霍奇金淋巴瘤。3例为单发，5例为多发，共13个病灶，其中大脑半球8个，基底节区4个，右侧背侧丘脑及基底节区1个。8例病变均表现为局灶性肿块，T1WI呈稍低或等信号；T2WI呈等或稍高信号。增强扫描7例呈明显均匀强化，1例轻度强化。6例瘤周重度水肿，2例瘤周中度水肿。结论原发性中枢神经系统淋巴瘤较为罕见，MRI是诊断该病的重要的无创性检查方法。颅内PCNSL影像学表现多样，但具有一定特征。

MRI findings of intracranial primary central nervous system lymphoma

Objective To study the MRI findings of intracranial primary central nervous system lymphoma （PCNSL）.Methods MRI findings of 8 patients with surgically and pathologically proved PCNSL were retrospectively analyzed.Results All 8 eases were diffuse large B cell non-Hodgkin＇s lymphoma, of whom,total 13 lesions comprised 3 cases of single lesion and 5 cases of multiple lesions.8 lesions locatcd in the serebral hemisphere,4 in basal ganglia,and lin the right dorsal thalamus and basal ganglia.All lesions appeared as localized masses.The lesions showed slightly hypointense to isointense signal on T1WI and isointense to slightly hyperintense signal on T2WI.After the administration of Gd-DTPA,markedly homogeneous enhancement and slight enhancement were found in 7 and 1 case, respectively.The peritumoral edema were found in all patients who comprised 6 severe and 2 moderate.Conclusion PCNSL is a clinically rare malignant tumor while MRI is a non-invasive means for diagnosing this disease.Ahhough intracranial PCNSL has various imaging findings,yet it has common feature of intracranial lymphoma.