神经纤维瘤病中枢神经系统的MRI表现

目的 探讨神经纤维瘤病(NF)的中枢神经系统(CNS)MR表现。方法 回顾性分析10例神经纤维瘤病患的临床资料并对其中枢神经系统MR表现进行分析，所有病例均行常规MR平扫及增强扫描。结果 10例病例中，NF—1型6例，表现为脑内胶质瘤、椎管内神经纤维瘤，4例合并皮肤损害，其中一例有家族史，NF—2型4例，表现为双侧听神经瘤、多发脑膜瘤或神经纤维瘤，皮肤损害少见。所有病例中增强扫描均发现平扫未发现之病灶。结论 MR能很好显示病变的大小、形态及信号特点，对检出神经纤维瘤病中枢神经系统的损害方面有优势，增强扫描可帮助发现平扫未见病灶。

MR imaging of neurofibromatosis in CNS

Objective To investigate the MRI findings of neurofibromatosis in central nerve system(CNS).Methods The clinical data and MR features of 10 patients with neurofibromatosis were analyzed retrospectively.Conventional MR plain scan and enhanced scan were performed in all patients.Results 6 of 10 cases were NF- 1 in which MR appearances included cerebral parenchymal glioma,intravertebral neurofibroma and associated with cutaneous lesions in 4 cases, had family history in 1 case.Other 4 cases with bilateral acoustic neuromas,multiple meningioma or neurofibroma were belonged to NF- 2 in which cutaneous lesions were seldom.Enhanced scan could show the lesions missed on plain scan.Conclusion MR can show the size, shape and signal features of neurofibromatosis lesions and therefore it has an important value for detecting the lesions in CNS whereas enhanced scan is helpful to show the lesions missed on plain scan.