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应用多元化定位和多靶点组合治疗强迫障碍的探讨
引用本文:姜克明,李拴德,王晓峰,杨来启,宋世田,张红宾,李涛,吴兴曲,马文涛,刘光雄.应用多元化定位和多靶点组合治疗强迫障碍的探讨[J].西北国防医学杂志,2002,23(6):411-413.
作者姓名:姜克明  李拴德  王晓峰  杨来启  宋世田  张红宾  李涛  吴兴曲  马文涛  刘光雄
作者单位:解放军第三医院,陕西,宝鸡,721004
基金项目:全军医学科研“十五”计划面上项目A类(0 1MA0 19),全军首批临床高新技术重大项目 (3 )
摘    要:目的 :研究多靶点组合对强迫障碍的治疗作用。方法 :采用立体定向方法 ,运用多元化定位和多靶点组合 ,射频热凝治疗强迫障碍 7例。采用总疗效评定量表 (GAS)和精神外科手术副反应量表 (PSESS)对照评估。结果 :7例强迫症中显效 3例 ,进步 4例。结论 :双侧扣带回 +双侧内囊前肢多靶点组合治疗 ,对难治性精神病的强迫症有明显的治疗作用

关 键 词:立体定向手术  强迫障碍  扣带回  内囊前肢
文章编号:1007-8622(2002)06-0411-03
修稿时间:2002年9月17日

Therapeutic efficacy on intractable obsessive-compulsive disorder with multielement location and multi-nucleus lesion
JIANG Ke-ming,LI Shuan-de,WANG Xiao-feng,et al..Therapeutic efficacy on intractable obsessive-compulsive disorder with multielement location and multi-nucleus lesion[J].Medical Journal of National Defending Forces in Northwest China,2002,23(6):411-413.
Authors:JIANG Ke-ming  LI Shuan-de  WANG Xiao-feng  
Affiliation:JIANG Ke-ming,LI Shuan-de,WANG Xiao-feng,et al .
Abstract:Objective:To study the therapeutic efficacy on intractable obsessive-compulsive disorder with multielement location and multi-nucleus lesion.Methods:7 patients with intractable obsessive-compulsive disorder were treated with stereotactic technique and multi-nucleus lesion. Global Assessment Scale (GAS) and Psychosurgery Treatment Emergent Symtom Scale (PSESS) were used to estimate the therapeutic efficacy.Results:3 cases appeared very effective and 4 cases were improved.Conclusion:The lesion of bilateral callosal gyrus and bilateral anterior limb of internal capsule might be an effective method to treat intractable obsessive-comlpulsive disorder.
Keywords:Stereotactic neurosurgery  Obsessive-compulsive disorder  Callosal gyrus  Anterior limb of internal capsule
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