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Mitochondrial encephalomyopathy (MELAS) with mental disorder
Authors:T Suzuki  J Koizumi  H Shiraishi  N Ishikawa  K Ofuku  M Sasaki  T Hori  N Ohkoshi  I Anno
Affiliation:(1) Department of Psychiatry Institute of Clinical Medicine, The University of Tsukuba, Japan;(2) Department of Neurology Institute of Clinical Medicine, The University of Tsukuba, Japan;(3) Department of Radiology, Institute of Clinical Medicine, The University of Tsukuba, Japan
Abstract:Summary A case of mitochondrial encephalomyopathy (MELAS) with mental disorder is reported. The SPECT study using123I-iodoamphetamine (IMP) and MRI study revealed abnormality in the left parieto-occipital areas without abnormality in the brain CT or brain scintigram. These findings suggest a localized dysfunction of the brain capillary endothelium in association with the cerebral involvement of mitochondrial encephalomyopathy.
Keywords:Mitochondrial encephalomyopathy  CT  MRI  SPECT
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