| 低剂量X射线全身照射诱导小鼠胸腺细胞CD3分子表达的适应性反应 |
| |
| 引用本文： | 鞠桂芝,苏旭,齐进,张迎春,刘树铮.低剂量X射线全身照射诱导小鼠胸腺细胞CD3分子表达的适应性反应[J].中华放射医学与防护杂志,1996,16(5):314-316. |
| |
| 作者姓名： | 鞠桂芝 苏旭 齐进 张迎春 刘树铮 |
| |
| 作者单位： | 130021 长春, 白求恩医科大学卫生部放射生物重点实验室;130021 长春, 白求恩医科大学卫生部放射生物重点实验室;130021 长春, 白求恩医科大学卫生部放射生物重点实验室;130021 长春, 白求恩医科大学卫生部放射生物重点实验室;130021 长春, 白求恩医科大学卫生部放射生物重点实验室 |
| |
| 摘 要： | 采用免疫荧光流式细胞术（ＦＣＭ）观察了昆明种小鼠胸腺细胞ＣＤ３分子表达的变化。首次报道了０．０７５ＧｙＸ射线单次全身照射可诱导小鼠胸腺细胞ＣＤ３分子表达对其后１．５Ｇｙ攻击剂量照射的适应性反应。证实，１．５Ｇｙ全身照射后胸腺ＣＤ３阳性细胞明显减少，照后１８小时仅为假照射组的３３．７４％。当１．５Ｇｙ照射前６小时预先照射０．０７５Ｇｙ时，可明显减轻其后攻击剂量对ＣＤ３分子表达的抑制作用，此时，ＣＤ３
|
| 关 键 词： | 低剂量辐射 适应性反应 CD3分子 表达 胸腺细胞 |
| 收稿时间： | 1996/2/26 0:00:00 |
| 修稿时间： | 1996/4/19 0:00:00 |
Adaptive response of CD3 expression of thymocytes in mice induced by low dose X-ray irradiation |
| |
| Ju Guizhi.Adaptive response of CD3 expression of thymocytes in mice induced by low dose X-ray irradiation[J].Chinese Journal of Radiological Medicine and Protection,1996,16(5):314-316. |
| |
| Authors: | Ju Guizhi |
| |
| Affiliation: | Department of Radiation Biology, Norman Bethune University of Medical Sciences, Changchun, 130021;Department of Radiation Biology, Norman Bethune University of Medical Sciences, Changchun, 130021;Department of Radiation Biology, Norman Bethune University of Medical Sciences, Changchun, 130021;Department of Radiation Biology, Norman Bethune University of Medical Sciences, Changchun, 130021;Department of Radiation Biology, Norman Bethune University of Medical Sciences, Changchun, 130021 |
| |
| Abstract: | Flow cytometry was used to analyze CD3 expression of thymocytes in mice for their immunofluorescence stained with monoclonal antibody.It was found that the adaptive response of CD3 expression of thymocytes could be induced by 0.075Gy (conditioning dose, D1) whole body X-irradiation which was delivered 6h before 1.5Gy (challenge dose,D2) exposure.The results showed that the number of CD cells of thymus was significantly higher in D1+ D2 guoup than that in D2 group (P< 0.01). |
| |
| Keywords: | Low dose radiation Adaptive response CD3 expression Thymocytes |
| 本文献已被 维普 等数据库收录！ |
| 点击此处可从《中华放射医学与防护杂志》浏览原始摘要信息 |
|
点击此处可从《中华放射医学与防护杂志》下载全文 |
|
