对比剂Gd-DTPA对肝外胆管癌磁共振扩散加权成像的影响 |
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引用本文: | 王余,王海平,韩德昌,马梦华,孙正君,.对比剂Gd-DTPA对肝外胆管癌磁共振扩散加权成像的影响[J].放射学实践,2012,27(4):421-424. |
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作者姓名: | 王余 王海平 韩德昌 马梦华 孙正君 |
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作者单位: | 王余 (唐山市工人医院核磁共振室, 河北,063000) ; 王海平 (唐山市工人医院核磁共振室, 河北,063000) ; 韩德昌 (唐山市工人医院核磁共振室, 河北,063000) ; 马梦华 (唐山市工人医院核磁共振室, 河北,063000) ; 孙正君 (唐山市工人医院核磁共振室, 河北,063000) ; |
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基金项目: | 2010年唐山市科学技术研究与发展计划指导项目 |
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摘 要: | 目的:探讨对比剂钆喷替酸葡甲胺(Gd-DTPA)对肝外胆管癌磁共振扩散加权成像(DWI)图像质量及表观扩散系数(ADC)的影响。方法:回顾性分析经病理证实并被DWI检出的57例肝外胆管癌患者的DWI图像资料,比较静脉注射对比剂Gd-DTPA增强前后及不同b值条件下肝外胆管癌病灶信噪比(SNR)、病灶与正常肝脏间对比信噪比(CNR)及ADC值的差异。结果:同一b值条件下,增强前后病灶SNR、CNR、ADC值的差异均无统计学意义(P>0.05);增强前后肝外胆管癌病灶SNR、CNR及ADC值均随着b值的增大而降低,其差异均有统计学意义(P<0.05)。结论:肝外胆管癌病灶的DWI图像质量及ADC值不受Gd-DTPA影响,所以选择合适b值的增强后DWI序列是可行的。
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关 键 词: | 胆管癌 扩散加权成像 钆喷替酸葡甲胺 |
The effect of using Gd-DTPA as contrast medium on diffusion weighted imaging for extrahepatic cholangiocarcinoma |
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Affiliation: | WANG Yu,WANG Hai-ping,HAN De-chang,et al.Department of MRI,Tangshan Worker′s Hospital,Tangshan,Hebei 063000,P.R.China |
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Abstract: | Objective:To evaluate the effect of Gd-DTPA as contrast medium for the image quality and apparent diffusion coefficient(ADC) on diffusion weighted imaging(DWI) of extra hepatic cholangiocarcinoma.Methods:The DWI materials of 57 patients with extrahepatic cholangiocarcinoma confirmed by pathology were analyzed retrospectively.The differences of signal-noise ratio(SNR) of tumor foci,contrast-noise ratio(CNR) of tumor foci and normal liver,ADC values of extrahepatic cholangiocarcinoma before and after administration of Gd-DTPA with different b values were measured and compared.Results:Of the same b value,no statistical significant differences were existed on SNR and CNR and ADC values of tumor foci before and after administration of Gd-DTPA(P0.05).As the b values increased,the SNR,CNR and ADC values of tumor foci before and after Gd-DTPA administration decreased gradually with significant statistical differences(P0.05).Conclusion:The DWI quality and ADC values were not influenced by Gd-DTPA administration,it is feasible to choose appropriate b value to perform DWI after administration of Gd-DTPA for the diagnosis of extrahepatic cholangiocarcinoma. |
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Keywords: | Cholangiocarcinoma Diffusion weighted imaging Gd-DTPA |
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