七氟醚与异氟醚吸入用于腹腔镜胆囊切除术麻醉效果比较

目的比较七氟醚和异氟醚用于腹腔镜胆囊切除术麻醉效果。方法42例腹腔镜胆囊切除术患者随机分为七氟醚组（S组）和异氟醚组（Ⅰ组），每组21例。快速诱导后麻醉维持两组分别吸入1MAC七氟醚和异氟醚，必要时追加芬太尼、罗库溴铵维持麻醉。记录诱导前（T0）、插管后5min（T1）、切皮（T2）、气腹开始（L）、缝皮（T4）、睁眼（T5）和拔管前（T6），患者的HR、SP、DP和SpO2。计算从停止吸入麻醉药到睁眼和拔管的时间。结果1MAC七氟醚和异氟醚对病人血流动力学指标的影响均较轻，组间比较差异无统计学意义，S组患者的睁眼时间和拔管时间均比I组短，组间比较差异具有统计学意义。结论七氟醚和异氟醚吸入麻醉对腹腔镜胆囊切除术患者心血管功能的影响程度相似，但七氟醚全麻患者苏醒时间和拔管时间均明显短于异氟醚全麻患者。

Clinical efficacy during sevoflurane,isoflurane anesthesia in the patients undergoing lapsroscopic surgery

Aim To investigate and compare the clinical efficacy of sevoflurane,isoflurane anesthesia in the patients undergoing lapsro- scopic surgery. Methods Fourty-two ASA Ⅰ or Ⅱ patients undergoing elective laparoscopic cholecystectomy were randomly divided into two groups ：sevoflurane group（ n = 21, group S） and isoflurane group（ n = 21, group I）. Anesthesia was maintained with 1 MAC end-tidal concent ration of sevoflurane or Isoflurane by continuous. HR, SP, DP and SpO2 were continuously measured throughout anesthesia. The time of open eyes and extubation was recorded. Results The hemedynamic status of all patients were little influenced by sevoflurane in S group or isoflurane in I group at 1 MAC. There were differences in the time of open eyes and extubation between group S and group I. Conclusion Inhalation of sevoflurane can affect hemodynamics in a similar degree to inhalation of isoflurane in the patients undergoing lapsroscopic surgery. But the time of open eye and extubation in group S were significantly shorter than those in group I.