尼卡地平防治腹腔镜手术CO_2气腹致循环不良反应的效果

目的应用尼卡地平在腹腔镜手术中CO2气腹的建立对循环系统产生不良反应的治疗及预防。方法腹腔镜胆囊切除术患者60例,随机分为试验组和对照组,试验组以尼卡地平10μg/kg静脉注射后,以微量泵维持泵入尼卡地平5μg/(kg·min)维持;对照组无特殊用药。结果试验组在心率(HR)和平均动脉血压(MAP)等血液动力学指标趋于稳定与对照组相比有明显的差异。结论尼卡地平可有效治疗和预防腹腔镜手术时CO2气腹对机体循环产生的不利影响,保证患者的麻醉安全。

The effects of nicardipine on preventing and treating hemodynamic disorders in laparoscopic surgery

Objective To evaluate the effects of nicardipine on preventing and treating the hemodynamic disorders caused by the creation of pneumoperitoneum in laparoscopic surgery.Method 60 patients to be undergone elective laparoscopic cholecystectomy were random divided into two groups: nicardipine group received a bolus injection of 10μg/kg and then a continuous infusion of 5μg/(kg·min) nicardipine intravenously; the control group received no special treatments. Results The hemodynamic parameters (including heart rate and mean blood pressure) were kept more stable in the nicardipine group and were prominently different from those in the control group.Conclusion Nicardipine can prevent and treat the hemodynamic disorders caused by the creation of pneumoperitoneum in laparoscopic surgery.