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氧氟沙星壳聚糖滴眼液的研制
引用本文:李平,张建林.氧氟沙星壳聚糖滴眼液的研制[J].中国生化药物杂志,1999,20(2):68-69.
作者姓名:李平  张建林
作者单位:兰州医学院第一附属医院药剂科!730000(李平,李家仁,常威),兰州市药品检验所(张建林),中国科学院兰州化学物理研究所(王爱勤,俞贤达)
摘    要:增强氧氟沙星疗效和降低其不良反应。方法:以壳聚糖为辅料,研制氧氟沙星壳聚糖滴眼液。结果:此制备工艺可行,内在质量稳定。采用紫外分光光度法测定该品含量.方法简便、准确.平均回收率99.75%,RSD=0.34%。结论:该品符合有关质量要求,可用于临床。

关 键 词:氧氟沙星  壳聚糖  滴眼液

The Preparation of Ofloxacin and Chitosan Eye Drops
Li Ping,Zhang Jianlin,Li Jiaren,Chang Wei,Wang Aiqin,Yu Xianda.The Preparation of Ofloxacin and Chitosan Eye Drops[J].Chinese Journal of Biochemical Pharmaceutics,1999,20(2):68-69.
Authors:Li Ping  Zhang Jianlin  Li Jiaren  Chang Wei  Wang Aiqin  Yu Xianda
Abstract:Purposc: The aim was to increse the therapy and reduce the adverse reactions of ofloxacin. Methods: Ofloxacin and chitosan eye drops was prepared with chitosan as material. Results: The preparation of oflxoacin and chitosan eye drops was practicable, the internal quality was stable. The content of this product was determined by UV spectrophotometry, it was convenient, accurate, average recovery was 99. 7%, RSD=0.34%. Conclusion:This eye drops was suitable to relative quantitative requiment, it may be used in clinic.
Keywords:Ofloxacin  Chitosan  Eye drops
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