| 氧化型细胞色素C注射液的制备及稳定性研究 |
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| 引用本文： | 崔慧斐,李华.氧化型细胞色素C注射液的制备及稳定性研究[J].中国生化药物杂志,1998,19(3):139-141. |
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| 作者姓名： | 崔慧斐 李华 |
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| 作者单位： | 山东医科大学生化制药教研室!济南，250012，山东医科大学生化制药教研室!济南，250012，山东医科大学生化制药教研室!济南，250012，山东医科大学生化制药教研室!济南，250012，莱阳生物化学制药厂 |
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| 摘 要： | 制备了氢化型细胞色素C注射液，利用热加速和光加速法研究了该制剂的稳定性，并与国产细胞色素C注射液及注射用细胞色素c冻干剂（均为还原型）对照。结果表明，所制备的氧化型细胞色素C注射液的热稳定性比后两者高，25℃贮存期分别为8、2．6及3年，光加速实验表明氧化型细胞色素C注射液对光亦较稳定。
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| 关 键 词： | 细胞色素C 制剂 稳定性 |
Preparation and Stability Study of Cytochrome C(Fe~(3 )) Injection |
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| Cui Huifei, Li Hua, Liang Libo, Cao Jichao, Xu Leifeng.Preparation and Stability Study of Cytochrome C(Fe~(3 )) Injection[J].Chinese Journal of Biochemical Pharmaceutics,1998,19(3):139-141. |
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| Authors: | Cui Huifei Li Hua Liang Libo Cao Jichao Xu Leifeng |
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| Abstract: | Cytochrome C (Fe3+) injection was preparared and its stability was studied with heat acceleration method and light acceleration method, meanwhile, contrasted with national Cytochrome C (Fe2+) injection and Cytochrome C (Fe2+) lyophilized preparation (also for injection). The results showed that the Cytochrome C (Fe3+) injection was rather stable to heat than the two Cytochrome C (Fe2+) preparations, with shelf-life of 25℃ were 8, 2.6 and 3a respectively. The Cytochrome C (Fe3+) injection was quite stable to light as well. |
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| Keywords: | Cytochrome C Preparation Stability |
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