Synthesis and quality control of [18F]T807 for tau PET imaging |
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| Authors: | Daniel P Holt Hayden T Ravert Robert F Dannals |
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| Affiliation: | Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA |
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| Abstract: | The detailed synthesis and quality control of 18F]T807, radiotracer for tau protein aggregate imaging, are described. The radiotracer synthesis was accomplished in an average of 48 min with an average specific activity at end‐of‐synthesis of over 4.4 TBq/µmole (120 Ci/µmole) and an average radiochemical yield of 32%. Compliance with all standard US Pharmacopeia Chapter <823> acceptance tests was observed. |
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| Keywords: | fluorine‐18 microwave tau PET quality control |
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