| 野蔷薇根化学成分的研究 |
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| 引用本文： | 都恒青,赵曦,赵天增,汪茂田,张占旺,姚苗,余守志.野蔷薇根化学成分的研究[J].药学学报,1983,18(4):314-316. |
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| 作者姓名： | 都恒青 赵曦 赵天增 汪茂田 张占旺 姚苗 余守志 |
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| 作者单位： | 河南省中医研究所 郑州
(都恒青，赵曦)，河南省化学研究所 郑州
(赵天增，汪茂田，张占旺，姚苗)，河南省化学研究所 郑州(余守志) |
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| 摘 要： | 野蔷薇根系蔷薇科植物多花蔷薇(Rosa multiflora Thunb.)的干燥根,民间用其除风湿、活气血和治疗乳糜尿。Takahashi等从野蔷薇根中分离出2α,19α-二羟基熊果酸(tomentic acid)。我们从野蔷薇根中分离出三个化合物,通过光谱和化学反应分别鉴定为β-谷甾醇,2α,19α-二羟基熊果酸,和2α,19α-二羟基熊果酸-(28-1)-β-D-
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| 关 键 词： | 多花蔷薇 三萜酸糖酯 野蔷薇甙 2α 19α-二羟基熊果酸 |
| 收稿时间： | 1982-02-08 |
STUDIES ON THE CHEMICAL CONSTITUENTS OF THE ROOTS OF ROSA MULTIFLORA THUNB |
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| DU Heng-qing,ZHAO Xi,ZHAO Tian-zeng,WANG Mao-tian,ZHANG Zhan-wang,YAO Miao and YU Shou-zhi.STUDIES ON THE CHEMICAL CONSTITUENTS OF THE ROOTS OF ROSA MULTIFLORA THUNB[J].Acta Pharmaceutica Sinica,1983,18(4):314-316. |
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| Authors: | DU Heng-qing ZHAO Xi ZHAO Tian-zeng WANG Mao-tian ZHANG Zhan-wang YAO Miao and YU Shou-zhi |
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| Abstract: | Three compounds were isolated from the roots of Rosa multiflora Thunb. They were identified to be β-sitosterol, 2α, 19α-dihydroxy ursolic acid (Ⅰ) and 2α, 19α-dihydroxy ursolic acid-(28-1)-β-D-glucopyranosyl ester (;dl2y spectroscopic analysis (UV, IR, MS, 1HNMR and 13CNMR) and chemical evidence. The third compound is a new triterpenoic acid sugar ester, named as rosamultin (Ⅱ), C36H58O10, mp 208～210℃, α]D=+10° (c=3.30, EtOH). In pharmacological and preliminary clinical tests the roots of Rosa multiflora Thunb exhibited hypolipidimic activity. |
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| Keywords: | Triterpenoic acid sugar ester Rosamultin Tormentic acid 2α 19α-Dihydroxy ursolic acid Rosa multiflora |
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