| 中药三七高效液相色谱特征研究 |
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| 引用本文： | 万建波,李绍平,王一涛.中药三七高效液相色谱特征研究[J].药学学报,2006,41(11):1090-1093. |
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| 作者姓名： | 万建波 李绍平 王一涛 |
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| 作者单位： | 澳门大学,中华医药研究所,澳门 |
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| 基金项目： | 澳门大学校科研和教改项目 |
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| 摘 要： | 目的建立中药三七的高效液相色谱特征谱。方法运用加压溶剂提取、HPLC-DAD分析28个不同产地的三七药材,所得的图谱采用中国药典委员会开发的“中药色谱指纹图谱相似度评价系统（Version 2004A）”软件进行分析。结果28个三七样品色谱图中各色谱峰分离良好,从中确定了13个特征峰,其中8个主要色谱峰经对照品确认,所有药材色谱图与软件生成的对照谱相似度为0.982±0.008(RSD=0.78%)。结论该方法简便、重现性好、具可操作性,可科学评价及有效控制三七药材质量。
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| 关 键 词： | 三七 人参皂苷 加压溶剂提取 相似度评价 |
| 文章编号： | 0513-4870（2006）11-1090-04 |
| 收稿时间： | 03 7 2006 12:00AM |
| 修稿时间： | 2006-03-07 |
RP-HPLC characteristics of Panax notoginseng |
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| WAN Jian-bo,LI Shao-ping,WANG Yi-tao.RP-HPLC characteristics of Panax notoginseng[J].Acta Pharmaceutica Sinica,2006,41(11):1090-1093. |
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| Authors: | WAN Jian-bo LI Shao-ping WANG Yi-tao |
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| Affiliation: | Institute of Chinese Medical Sciences, University of Macau, Macau, China. |
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| Abstract: | AIM: To develop the chemical characteristics of Panax notoginseng in order to control its quality. METHODS: The samples was extracted using pressurized liquid extraction (PLE) and analyzed by HPLC-DAD. The data were evaluated using the "similarity evaluation system for chromatographic fingerprint of TCM" software (version 2004A). RESULTS: The chromatographic characteristics of 28 Panax notoginseng from different places were established using HPLC-DAD, and 8 peaks among 13 typical ones in the chromatograms were identified by comparing with their reference compounds. The similarity of different samples was high (0.982 +/- 0.008, RSD = 0.78%). CONCLUSION: The chromatographic characteristics are useful to control the quality of Panax notoginseng. |
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| Keywords: | Panax notoginseng ginsenoside pressurized liquid extraction similarity evaluation |
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