| 紫外分光光度法测定阿奇霉素干混悬剂的含量 |
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| 引用本文： | 汪锦飘,林茵,马再鸿.紫外分光光度法测定阿奇霉素干混悬剂的含量[J].中国实用医药,2008,3(4):46-47. |
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| 作者姓名： | 汪锦飘 林茵 马再鸿 |
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| 作者单位： | 中山大学附属第二医院临床药学部,广州,510120 |
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| 摘 要： | 目的建立紫外分光光度法测定阿奇霉素干混悬剂的含量。方法依据阿奇霉素与硫酸溶液（75→100）在pH值6．0的磷酸盐缓冲液中反应生成的络合物的光谱特征，选择482nm作为测定波长。结果阿奇霉素浓度在16～96μg／ml之间与吸收度呈良好线性关系（r=0．9997），平均回收率为99．3％（n=5），RSD为0．7％。结论本方法快速、简便，结果准确。
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| 关 键 词： | 阿奇霉素干混悬剂 紫外分光光度法 含量测定 |
Determination of caulsuspension's concentration of azithromycin by colorimetry method |
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| WANG Jin-piao,LIN Yin,MA Zai-hong.Determination of caulsuspension's concentration of azithromycin by colorimetry method[J].China Practical Medical,2008,3(4):46-47. |
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| Authors: | WANG Jin-piao LIN Yin MA Zai-hong |
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| Affiliation: | .( The Second Hospital Affiliated to Zhongshan University, Guangzhou Guangdong Province 510120, China) |
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| Abstract: | Objective To establish caulsuspension＇ s concentration of Azithromycin by colorimetry method. Methods Choose determine wavelength at 482 nm on the basis of Azithromycin reacted with sulfuric acid solution（75→100）,PB （pH = 6. 0）and generated comoles compound＇s optical spectrum characters. Resuits Azithromycin （ 16-96 μg/ml） showed fine linear relationship （ r = 0. 9997 ） with absorbability, average recovery was 99.3% （ n = 5 ） , RSD = 0.7%. Conclusion The method is quick, simple and accurate. |
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| Keywords: | Caulsuspension＇ s concentration of Azlthromycin Colorimetry method Assaying |
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