我院206例药品不良反应报告调查

目的：了解我院药品不良反应（ADR）发生的特点。方法：对我院上报的206例ADR报告,从患者一般情况、ADR涉及药品种类、涉及器官或系统及临床表现等方面进行回顾性分析。结果：206例ADR中,50岁以上中老年患者居多,占48.06%;抗菌药物引起的ADR最多见,占44.17%,其次为中药制剂,占15.05%,其中注射剂占90.32%;给药途径以静脉给药最多,占62.62%;涉及器官及系统以皮肤及其附件最多,占46.12%。结论：应加强中老年患者的用药监护,降低静脉给药比率,提高抗菌药物及中药注射剂的合理使用水平,以减少ADR的发生。

Investigation of 206 Reports of Adverse Drug Reactions in our Hospital

Objective：To understand the characteristics and laws of adverse drug reaction（ADR）in our hospital. Methods：206 ADR cases were collected in our hospital in respect of patients＇ general condition,types of drugs,organs and systems involved and clinical manifestation.Results：Of the 206 ADR cases,elderly patients above 50 years old was in the majority（48.06%）;ADRs induced by antibacterial drugs were the most common（44.17%）,followed by traditional Chinese drugs preparations（15.05%）,in which injections accounted for the vast majority（90.32%）,and the intravenous administration was the most main route（62.62%）.Lesions of skin and its appendixes were the main clinical manifestations（46.12%）.Conclusion：The drug monitoring in elderly patients should be strengthened to reduce the ratio of intravenous administration,enhance the level of rational use of antibacterial drugs and traditional Chinese medicine injections in order to reduce the ADR occurrence.