美沙拉秦灌肠液联合布拉氏酵母菌散治疗溃疡性结肠炎的疗效观察

目的：探讨美沙拉秦灌肠液联合布拉氏酵母菌散治疗溃疡性结肠炎的临床效果。方法选择本院2013年7月—2014年4月收治的轻、中度活动性溃疡性结肠炎患者80例，随机分为治疗组和对照组，各40例。治疗组给予美沙拉秦灌肠液联合布拉氏酵母菌散治疗，对照组仅给予美沙拉秦灌肠液治疗。观察两组患者的临床效果及不良反应。结果治疗后，治疗组总有效率为97.5%（39/40），高于对照组的77.5%（31/40），差异有统计学意义（P〈0.05）。两组患者的不良反应未通过特殊处理均自行缓解。结论美沙拉秦灌肠液联合布拉氏酵母菌散治疗溃疡性结肠炎疗效确切。

Clinical Effect of Mesalazine Enema Liquid and Saccharomyces Boulardii Sachet in the Treatment Ulcerative Colitis

Objective To investigate the clinical efficacy of mesalazine enema liquid and saccharomyces boulardii sa-chet treating ulcerative colitis. Methods 80 patients with mild-moderate ulcerative colitis in our hospital from July 2013 to A-pril 2014,were randomly divided into treatment group（n=40）and the control group（n=40）. The treatment group was trea-ted with mesalazine enema liquid and saccharomyces boulardii sachet,while the control group was treated with mesalazine enema liquid. The clinical effect and adverse reaction of two groups were compared. Results After treatment,the effective rate of treatment group was 97. 5%（39/40）,which was higher than that of control group of 77. 5%（31/40）,the difference was sta-tistically significant（ P〈0. 05）. Adverse reactions of the two groups were relieved itself without special treatment. Conclusion The effect of mesalazine enema liquid and saccharomyces boulardii sachet in treating ulcerative colitis is remarkable.