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清开灵注射液与输液配伍的稳定性研究
引用本文:陈颖,曹烨民,堵玉萍,钱晓琴.清开灵注射液与输液配伍的稳定性研究[J].临床合理用药杂志,2009,2(6):30-31.
作者姓名:陈颖  曹烨民  堵玉萍  钱晓琴
作者单位:上海市中西医结合医院药剂科,200082
基金项目:上海市虹口区卫生系统科研基金重点项目
摘    要:目的研究清开灵注射液与输液配伍的稳定性。方法用显微计数法分别测定清开灵注射液与输液配伍前后药液的不溶性微粒数。结果配伍溶液中不溶性微粒显著多于配伍前(P〈0.05),不溶性微粒的数量与放置时间无相关性(P〉0.05)。结论清开灵注射液与输液配伍后稳定性在规定限度内,仍可能诱发药物不良反应,应引起重视。

关 键 词:清开灵  配伍  稳定性

The study of compatible stability of Qingkailing injection and infusion
Affiliation:CHEN Ying, CAO Ye-min, DU Yu-ping,et al.(Department of Pharmacy, Integrative Medicine Hospital of Shanghai City, Shanghai 200082, China)
Abstract:Objective To investgate the stability of Qingkailing injection mixed with infusion. Methods By using microscope counter the amount of insoluble particles in Qingkailing injections and the liquid mixed by Qingkailing injections and transfusion fluids. Results The nsoluble particles in mixture increased obviously ( P 〈 0. 05 ). The amount of insoluble particles have no relativity with time( P 〉 0.05 ). Conclusion The compatible stability of the mixture including Qingkailing injections and transfusion fluids is in the stated limit, however it may bring adverse reaction of drug . It should be regarded.
Keywords:Qingkailing injection  Compatibility  Stability
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