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| 中药黄独的化学成分 | |
| 引用本文： | 高慧媛,隋安丽,陈艺虹,张晓燕,吴立军.中药黄独的化学成分[J].沈阳药科大学学报,2003,20(3):178-180. |
| 作者姓名： | 高慧媛 隋安丽 陈艺虹 张晓燕 吴立军 |
| 作者单位： | 1. 沈阳药科大学中药学院,辽宁,沈阳,110016 2. 北京诺华制药有限公司,北京,100004 3. 东宇药业有限公司,辽宁,沈阳,110013 |
| 摘 要： | 目的对从中药黄独 (DioscoreabulbiferaL .)乙醇 (w =0 75 )提取物的乙酸乙酯萃取部分分离得到 5个化合物进行结构鉴定。方法采用硅胶柱色谱、高效液相色谱法进行分离 ,利用理化性质和谱学分析 ,鉴定分离得到的化合物结构。结果从中分得的 5个化合物其结构鉴定为 3,5 ,3′ 三甲氧基槲皮素 ( 3,5 ,3′ trimethoxyquercetin ,Ⅰ )、山奈酚 3 O β D 吡喃半乳糖苷 (kaempferol 3 O β D galactopyranoside ,Ⅱ )、香草酸 (vanillicacid ,Ⅲ )、异香草酸 (isovanillicacid ,Ⅳ )及 ( + )表儿茶素( ( + )epicatechin ,Ⅴ )。结论化合物Ⅰ、Ⅱ为首次从薯蓣属植物中分得的已知化合物 ,Ⅲ、Ⅳ为首次从黄独中分离得到的已知化合物 |
| 关 键 词： | 中药黄独 黄酮 有机酸 薯蓣属 |
| 文章编号： | 1006-2858(2003)03-0178-03 |
| 修稿时间： | 2002年10月10 |
Chemical constituents of Dioscorea bulbifera L. |
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| GAO Hui yuan ,SUI An li ,CHEN Yi hong ,ZHANG Xiao yan ,WU Li jun.Chemical constituents of Dioscorea bulbifera L.[J].Journal of Shenyang Pharmaceutical University,2003,20(3):178-180. | |
| Authors: | GAO Hui yuan SUI An li CHEN Yi hong ZHANG Xiao yan WU Li jun |
| Affiliation: | GAO Hui yuan 1,SUI An li 2,CHEN Yi hong 1,ZHANG Xiao yan 3,WU Li jun 1 |
| Abstract: | Objective To isolate and identify the compounds from the EtOAC partitioned fraction of 75% EtOH ( w =0 75) extract of Dioscorea bulbifera L.Methods Compounds were isolated by the silica gel columns and HPLC,and their structures were identified by the physical and chemical characters especially by the spectral analysis.Results Five compounds were obtained and they were identified as 3,5,3′ trimethoxyquercetin (Ⅰ),kaempferol 3 O β D galactoside (Ⅱ),vanillic acid (Ⅲ),isovanillic acid (Ⅳ) and (+)epicatechine (Ⅴ).Conclusions CompoundsⅠandⅡfrom Dioscorea genus and compounds Ⅲ and Ⅳ from Dioscorea bulbifera L.are obtained for the first time. |
| Keywords: | Dioscorea bulbifera L phenolic acid flavonoids Dioscorea |
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