| PLA-PEG嵌段共聚物在药物释放系统中的应用 |
| |
| 引用本文： | 虞阳,涂家生,张明,李朋梅.PLA-PEG嵌段共聚物在药物释放系统中的应用[J].药学进展,2005,29(6):250-254. |
| |
| 作者姓名： | 虞阳 涂家生 张明 李朋梅 |
| |
| 作者单位： | 中国药科大学药剂学教研室,江苏,南京,210009 |
| |
| 摘 要： | 介绍PLA-PEG嵌段共聚物的合成和性质,综述其作为胶束、微球、纳米粒等的载体在药物释放系统中的应用。聚乳酸-聚乙二醇嵌段共聚物因具备良好的生物可降解性和相容性而得到广泛应用。
|
| 关 键 词： | 聚乳酸-聚乙二醇 嵌段共聚物 生物可降解性 药物释放系统 |
| 文章编号： | 1001-5094(2005)06-0250-05 |
| 修稿时间： | 2004年11月23 |
Applications of PLA-PEG Block Copolymers in Drug Delivery System |
| |
| YU Yang,TU Jia-sheng,ZHANG Ming,LI Peng-mei.Applications of PLA-PEG Block Copolymers in Drug Delivery System[J].Progress in Pharmaceutical Sciences,2005,29(6):250-254. |
| |
| Authors: | YU Yang TU Jia-sheng ZHANG Ming LI Peng-mei |
| |
| Affiliation: | YU Yang,TU Jia-sheng~*,ZHANG Ming,LI Peng-mei |
| |
| Abstract: | Syntheses and properties of PLA-PEG block copolymers were introduced, and their applications for micelles,microspheres and nanoparticles in drug delivery system were also reviewed. Recently, poly(d,l-lactide)-poly(ethylene glycol) (PLA-PEG)block copolymers have been widely applied owing to the favorable biodegradability and biocompatibility. |
| |
| Keywords: | PLA-PEG Block copolymer Biodegradability Drug delivery system |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
