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头孢菌素类药物对尿糖测定的干扰研究
引用本文:周天杰,鄢德俊.头孢菌素类药物对尿糖测定的干扰研究[J].华西药学杂志,1994,9(2):84-87.
作者姓名:周天杰  鄢德俊
作者单位:华西医科大学职防院药剂科
摘    要:本文研究了8种(包括第一、二、三代)头孢菌素类药物对斑氏试验法及葡萄糖氧化酶试纸法测定尿糖的影响。结果表明,头孢菌素类药物能干扰斑氏法测定结果,干扰作用与被测液中药物浓度和葡萄糖浓度有关。该类药物对葡萄糖氧化酶试纸法测定尿糖无影响。

关 键 词:斑氏试验  头孢菌素  尿糖

STUDY ON INTERFERENCE WITH URINARY GLUCOSE DETERMINATION BY CEPHALOSPORINS
Zhou Tianjie,Yan Dejun,Cheng Xiaoning,Guo Jiongying, Zhao Jingsong.STUDY ON INTERFERENCE WITH URINARY GLUCOSE DETERMINATION BY CEPHALOSPORINS[J].West China Journal of Pharmaceutical Sciences,1994,9(2):84-87.
Authors:Zhou Tianjie  Yan Dejun  Cheng Xiaoning  Guo Jiongying  Zhao Jingsong
Abstract:The effect of cephalosporins(cefradine, cefazolin,cefotaxime, ceftizoxime,cefuroxime,ceftazidime,cefoperazone,ceftriaxone)on the accuracy of Benedict's and the glueose oxidase paper test determinations of glycosuria was studied.Falsely elevated Benedict's readings were obtained with the cephalosporins.These readings were influenced by the concentration of the cephalosporins and glucose.These drugs didn't interfere with glucose oxidase paper test reading.Because the Benedict-cephalosporins interaction is unpredictable,Benedict result should be rechecked using glucose oxidase paper test for glycosuria in patients receiving cephalosporins.
Keywords:Benedict's Cephalosporins Drug interaetions Glucose oxidase paper test Glycosuria
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