| 白花蛇舌草总黄酮体外对人肝癌细胞HepG-2的作用 |
| |
| 引用本文： | 周忆新,吴杨,顾珉.白花蛇舌草总黄酮体外对人肝癌细胞HepG-2的作用[J].抗感染药学,2009,6(3):179-181. |
| |
| 作者姓名： | 周忆新 吴杨 顾珉 |
| |
| 作者单位： | 1. 江苏省苏州药品检验所,江苏,苏州,215002
2. 惠氏制药有限公司,江苏,苏州,215000 |
| |
| 摘 要： | 目的:观察白花蛇舌草总黄酮体外对HepG-2肿瘤细胞增殖的抑制作用。方法:以HepG-2细胞为实验细胞株,观察白花蛇舌草中的总黄酮对HepG-2肿瘤细胞形态的影响;用流式细胞仪检测细胞的凋亡。结果:白花蛇舌草总黄酮对HepG-2肿瘤细胞形态有影响,抑制其生长并诱导HepG-2肿瘤细胞的调亡。结论:白花蛇舌草中的总黄酮通过诱导凋亡对人肝癌细胞HepG-2有抑制增殖作用。
|
| 关 键 词： | 白花蛇舌草 总黄酮 HepG-2细胞 凋亡 |
Effect of Flavone from Oldenlandia Diffusa (Willd.) Roxb.on Human Hepatoma Carcinoma Cell HepG-2 in vitro |
| |
| ZHOU Yi-Xin,WU Yang,GU Min.Effect of Flavone from Oldenlandia Diffusa (Willd.) Roxb.on Human Hepatoma Carcinoma Cell HepG-2 in vitro[J].Anti-infection Pharmacy,2009,6(3):179-181. |
| |
| Authors: | ZHOU Yi-Xin WU Yang GU Min |
| |
| Affiliation: | 1 Jiangsu Suzhou Institute For Drug Control, Suzhou Jiangsu 215002, China; 2Wyeth Pharmaceutical Co., Ltd, Suzhou Jiangsu 215000, China) |
| |
| Abstract: | Objectives： To observe the inhibiting effect of flavone from Oldenlandia diffusa（willd.） Roxb. on HepG-2 cell in vitro. Methods： The effect of cell growth inhibition was observed through the cell shape and apoptosis was assessed by flow cytometry. Results： The flavone from Oldenlandia diffusa（willd.）Roxb. inhibited HepG-2 cell growth and induce apoptosis. Conclusion： The flavone from Oldenlandia diffusa（willd.） Roxb. inhibit HepG-2 cell by induction of apoptosis. |
| |
| Keywords: | Oldenlandia diffusa （willd ） Roxb FOD HepG-2cell apoptosis |
| 本文献已被 维普 万方数据 等数据库收录！ |
