系数倍率法测定呋喃西林炉甘石洗剂中呋喃西林和苯酚的含量

目的:建立呋喃西林炉甘石洗剂中呋喃西林和苯酚的含量测定方法。方法:采用系数倍率法,在波长(λ)260nm和269nm不经分离直接测定呋喃西林炉甘石洗剂中两组分的含量。结果:呋喃西林在浓度(C呋)4.10～28.57μg/mL范围内与吸光度(A呋)的线性关系良好(r呋=0.9997),平均回收率为100.46%,RSD2.25%(n=5);苯酚在浓度(C苯)4.04～28.03μg/mL范围内与吸光度(A苯)的线性关系良好(r苯=0.9999);平均回收率为100.93%,RSD1.92%(n=5)。结论:测定方法简便、快速、准确,适用于该制剂的快速检验。

Determinaton of Furacilin & Phenol in Furacilin and Calamine Lotion by K-ratio Spectrophotometry

Objective： To establish a method for determining the content of furacilin and phenol in furacilin and calamine lotion. Methods： The concentrations of the two components in furacilin and calamine lotion were directly determined at wavelength 260nm and 269nm by K-ratio speetrophotometry without separation. Results： Furacilin presented a good linear relationship within a range of4.10-28.57 μg/mL（r = 0.999 7）.The average recovery was 100.46%, with RSD of 2.25%（n = 5）; Phenol presented a good linear relationship within a range of 4.04-28.03 μg/mL（r = 0.999 9）. The average recovery was 100.93%, with RSD of 1.92%（n = 5）. Conclusion： The method is simple, rapid and accurate. It is suitable for rapid assay of the preparation.