| 氟氯西林钠与4种输液的配伍稳定性 |
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| 引用本文： | 谢兵,吴明钗,林洁,陈晓孩.氟氯西林钠与4种输液的配伍稳定性[J].海峡药学,2010,22(6):57-59. |
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| 作者姓名： | 谢兵 吴明钗 林洁 陈晓孩 |
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| 作者单位： | 温州医学院附属第三医院,瑞安,325200 |
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| 摘 要： | 目的考察氟氯西林钠与果糖氯化钠、果糖、5%葡萄糖、转化糖四种输液的配伍稳定性。方法氟氯西林钠分别与4种输液配伍后放置于30℃恒温水浴箱,观察配伍溶液6h内的外观、pH值及氟氯西林的含量变化。结果氟氯西林与果糖氯化钠、果糖、5%葡萄糖、转化糖4种输液的配伍液在6h内其外观性状、pH值、氟氯西林的含量均无明显改变。结论氟氯西林钠与果糖氯化钠、果糖、5%葡萄糖、转化糖4种输液的配伍液在6h内稳定。
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| 关 键 词： | 氟氯西林钠 高效液相色谱法 配伍稳定性 |
The stability of flucloxacillin sodium for injection when mixed with four injection |
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| XIE Bing,WU Ming-chai,LIN Jie,CHEN Xiao-hai.The stability of flucloxacillin sodium for injection when mixed with four injection[J].Strait Pharmaceutical Journal,2010,22(6):57-59. |
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| Authors: | XIE Bing WU Ming-chai LIN Jie CHEN Xiao-hai |
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| Affiliation: | (The Third Affiliated Hospital of Wenzhou Medical College,Rui＇an 325200,China) |
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| Abstract: | OBJECTIVE To study the stability of flucloxacillin sodium for injection when mixed with fructose sodium chloride injection,fructose injection,5% glucose injection,inverl sugar injection.METHOES Flucloxacillin sodium mixed with four kinds of injection were put in water bath box separately,and then observe the changes of appearance,pH value and the content of flucloxacillin sodium.RESULTS No significant changes in the mixture of flucloxacillin sodium for injection and 5% glucose injection,fructose sodium chloride injection,fructose injection and inverl sugar injection in 6 hours.CONCLUSION The mixture of flucloxacillin sodium for injection and four injections are fundamentally stable. |
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| Keywords: | Flucloxacillin sodium HPLC Compatibility stability |
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