| 甘草酸二铵治疗抗精神病药物所致无黄疸型肝损害的对照研究 |
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| 引用本文： | 姜秀举,刘永明.甘草酸二铵治疗抗精神病药物所致无黄疸型肝损害的对照研究[J].中国当代医药,2011,18(6):37-38. |
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| 作者姓名： | 姜秀举 刘永明 |
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| 作者单位： | 江西省精神病院,江西南昌,330029 |
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| 摘 要： | 目的：探讨抗精神病药物所致无黄疸型肝损害的安全、有效地治疗方法。方法：将服用抗精神病药物致无黄疸型肝损害的60例住院精神病患者随机分为两组,甘草酸二铵组30例,护肝片组30例,疗程均为6周。观察治疗前后肝功能指标的变化。结果：甘草酸二铵组治愈率、总有效率分别为66.6%、90.0%,对照组治愈率、总有效率分别为46.6%、76.6%,差异均有统计学意义（P〈0.05）。两组治疗后肝功能指标均有改善,与治疗前比较,差异有统计学意义（P〈0.05）;两组肝功能治疗后比较差异有统计学意义（P〈0.05）。结论：甘草酸二铵能有效治疗抗精神病药物所致的无黄疸型肝损害。
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| 关 键 词： | 抗精神病药物 无黄疸型肝损害 甘草酸二铵 护肝片 |
Comparative study on the decoction of peony and liquorice in treating constipation due to antipsychotic medication |
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| Authors: | JIANG Xiuju LIU Yongming |
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| Affiliation: | (Mental Hospital of Jiangxi Province, Nanchang 330029, China) |
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| Abstract: | Objective： To study a safe and effective method for treating antipsychotic medication-induced constipation. Methods： 87 psychotic in-patients with antipsychotic medication-induced constipation were randomly divided into two groups： the decoction of peony and liquorice group （n=30）,the phenolphthalein group （n=30）. The therapeutic effects were observed and compared after administration. Results： There was significant difference in the therapeutic effects between the two groups （P0.05）. Conclusion： Decoction of peony and liquorice can effectively treat antipsychotic medication-induced constipation without side-effect. |
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| Keywords: | Antipsychotic medication Constipation Decoction of peony and liquorice Phenolphthalein |
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