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正交设计研究穿心莲中脱水穿心莲内酯提取工艺
引用本文:卓菊,汪小根.正交设计研究穿心莲中脱水穿心莲内酯提取工艺[J].中南药学,2005,3(3):155-157.
作者姓名:卓菊  汪小根
作者单位:广东化工制药职业技术学院,广州,510520
摘    要:目的优选穿心莲最佳提取工艺.方法用正交试验法,以提取液中脱水穿心莲内酯含量为考察指标,对影响内酯提取工艺的因素进行了研究.结果实验设计三因素中乙醇浓度、收集漉液倍数、浸渍时间均有显著影响.结论穿心莲最佳提取工艺为A1B2C2 ,即用95%的乙醇,浸渍24 h,收集9倍量的渗漉液.

关 键 词:正交实验  穿心莲  提取工艺
文章编号:1672-2981(2005)03-0155-03

Eextraction of Andrographis paniculata by orthogonal experiments
Zhuo Ju,Wang Xiao-gen.Eextraction of Andrographis paniculata by orthogonal experiments[J].Central South Pharmacy,2005,3(3):155-157.
Authors:Zhuo Ju  Wang Xiao-gen
Abstract:OBJECTIVE To optimize the conditions for the extraction of Andrographis paniculata.METHODS Conditions for the extraction were studied by the orthogonal experimental design as guided by the content of 14-deoxy-11-oxoandrographolide present in the extract.RESULTS Significant effect was observed in 3 different experimental conditions.CONCLUSIONS The optimum conditions for the extraction of Andrographis paniculata was soaking the drug in 95% alcohol for 24 hours and then collecting the percolating liquid corresponding to about 9 times of the quantity of Androyraphis paniculata.
Keywords:orthogonal experiment  Andrographis paniculata  extraction process
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