| 头孢唑林对阿米卡星在兔体内的药动学影响 |
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| 引用本文： | 阚全程,张晓坚.头孢唑林对阿米卡星在兔体内的药动学影响[J].中国抗生素杂志,1999,24(5):365-367. |
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| 作者姓名： | 阚全程 张晓坚 |
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| 作者单位： | 河南医科大学第一附属医院药剂科!郑州450052 |
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| 摘 要： | 采用微量微生物法对阿米卡星（ＡＭＫ）单用及与头孢唑林（ＣＥＺ）合用后兔体内ＡＭＫ血药浓度进行测定，药时数据用ＭＣＰＫＰ软件经ＩＢＭ 计算机处理，并对两组药动学参数进行了统计学处理，结果表明ＣＥＺ对ＡＭＫ的药动学有显著的影响。
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| 关 键 词： | 阿米卡星 头孢唑林 兔 联用 药动学 |
Influence of cefazolin on pharmacokinetics of amikacin on rabbits |
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| Kan Quancheng,Zhang Xiaojian and Shi Xiuqin.Influence of cefazolin on pharmacokinetics of amikacin on rabbits[J].Chinese Journal of Antibiotics,1999,24(5):365-367. |
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| Authors: | Kan Quancheng Zhang Xiaojian and Shi Xiuqin |
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| Abstract: | Amikacin (AMK) in the serum of rabbits was determined by the modified microbiological method and was compared with combination of AMK and cefazolin (CEZ). The concentration time were disposed with MCPKP program and IBM microcomputer. The results showed that CEZ had apparently influence on pharmacokinetics of AMK in rabbits. |
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| Keywords: | Amikacin Cefazolin Rabbit Combination Pharmacokinetics |
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