| 恶性血液病并发肺部感染的病原菌构成及耐药性变迁 |
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| 引用本文： | 洪攀,陆明钢.恶性血液病并发肺部感染的病原菌构成及耐药性变迁[J].中国药房,2011(30):2831-2833. |
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| 作者姓名： | 洪攀 陆明钢 |
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| 作者单位： | 浙江绍兴市人民医院血液科;浙江绍兴市人民医院检验科; |
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| 摘 要： | 目的:明确恶性血液病并发肺部感染的病原菌构成及耐药性变迁。方法:分析近5年来115例恶性血液病并发肺部感染患者的病原学和药敏学特点。结果:培养出病原菌242株,其中革兰阴性(G-)菌158株,排在前4位分别是铜绿假单胞菌、肺炎克雷伯菌、大肠埃希菌和嗜麦芽寡养单胞菌。铜绿假单胞菌对亚胺培南、头孢哌酮/舒巴坦、哌拉西林/他唑巴坦和阿米卡星的耐药率<30%;肺炎克雷伯菌和大肠埃希菌对亚胺培南、头孢哌酮/舒巴坦和哌拉西林/他唑巴坦的耐药率<30%;头孢哌酮/舒巴坦和复方磺胺甲唑对嗜麦芽寡养单胞菌有一定的抗菌活性。革兰阳性(G+)菌56株,耐药性严重,对万古霉素和替考拉宁敏感率均为100%。近5年来无论是G-菌还是G+菌的耐药率总体呈上升趋势。结论:恶性血液病并发肺部感染患者的主要病原菌为G-菌,呈现出多重耐药性,且耐药率不断增加。
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| 关 键 词： | 恶性血液病 肺部感染 病原菌 药敏试验 耐药性 |
Constitution and Drug Resistance of Pathogenic Bacteria of Malignant Hematology with Pulmonary Infection |
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| HONG Pan LU Ming-gang.Constitution and Drug Resistance of Pathogenic Bacteria of Malignant Hematology with Pulmonary Infection[J].China Pharmacy,2011(30):2831-2833. |
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| Authors: | HONG Pan LU Ming-gang |
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| Affiliation: | HONG Pan(Dept.of Hematology,Shaoxing People's Hospital of Zhejiang Province,Shaoxing 312000,China) LU Ming-gang(Dept.of Clinic Laboratory,China) |
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| Abstract: | OBJECTIVE:To identify the constitution and drug resistances of pathogenic bacteria of malignant hematology with pulmonary infection.METHODS:The etiology and drug sensitivity of 115 cases of malignant hematology with pulmonary infection were analyzed.RESULTS:242 strains of pathogenic bacteria were cultured.There were 158 strains of gram-negative bacteria.Top 4 were Pseudomonas aeruginosa,Klebsiella pneumoniae,Escherichia coli and Stenotrophomonas maltophilia.The drug resistance rates of Pseudomonas aeruginos... |
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| Keywords: | Malignant hematology Pulmonary infection Pathogenic bacteria Drug sensitivity test Drug resistance |
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