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复方甘草酸苷治疗慢性乙型肝炎的临床疗效观察
引用本文:颜宁.复方甘草酸苷治疗慢性乙型肝炎的临床疗效观察[J].中国药房,2004,15(6):355-356.
作者姓名:颜宁
作者单位:南京医科大学附属第一医院感染科,南京市,210006
摘    要:目的 :观察复方甘草酸苷对慢性乙型肝炎的临床疗效。方法 :用复方甘草酸苷及甘草酸二铵治疗43例慢性乙型肝炎 ,随机分组 ,治疗组 (复方甘草酸苷 )21例 ,对照组 (甘草酸二铵 )22例 ,用药12周后观察两组的临床症状、体征、肝功能指标变化及副作用。结果 :治疗组在总胆红素、ALT、AST的改善方面较对照组差异无显著性 (P>0 05) ,而副作用治疗组则明显小于对照组。结论 :复方甘草酸苷治疗慢性乙型肝炎及其他肝损安全、有效 ,其临床应用效果略优于甘草酸二铵。

关 键 词:复方甘草酸苷  慢性乙型肝炎  临床疗效
文章编号:1001-0408(2004)06-0355-02
修稿时间:2004年3月29日

Observation of the Therapeutic Effect of Compound Glycyrrhizin Injection on Chronic Hepatitis B
YAN Ning.Observation of the Therapeutic Effect of Compound Glycyrrhizin Injection on Chronic Hepatitis B[J].China Pharmacy,2004,15(6):355-356.
Authors:YAN Ning
Abstract:OBJECTIVE:To observe the therapeutic effect of compound glycyrrhizin injection(CG)on chronic hepatitis B(CHB).METHODS:45 patients with CHB were randomly divided into trial group(21 cases)and control group(22 cases)who received CG and diammonium glycyrrhizinate injection(DG)respectively.The changes of clinical symptoms,signs,liver function parameters and adverse reactions were observed after 12-week treatment.RESULTS:There were no significant differences in improvements of total bilirubin,ALT and AST between 2 groups(P>0.05),however,adverse reactions in trial group were obviously less than those in control group.CONCLUSION:CG is effecacious and safe in the treatment of CHB and other damage of liver and its clinical efficacy is better than that of DG.
Keywords:compound glycyrrhizin injection  chronic hepatitis B  clinical efficacy
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