| 灵芝孢子粉与子实体中三萜类化合物、多糖及重金属元素的含量比较 |
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| 引用本文： | 陈军辉,吴凤琪,李文龙,黎先春,王小如,张定,黄建寅.灵芝孢子粉与子实体中三萜类化合物、多糖及重金属元素的含量比较[J].中国药房,2008,19(33):2585-2587. |
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| 作者姓名： | 陈军辉 吴凤琪 李文龙 黎先春 王小如 张定 黄建寅 |
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| 作者单位： | 中国海洋大学化学化工学院，国家海洋局第一海洋研究所/青岛市现代分析技术及中药标准化重点实验室，Penta Biotech Inc |
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| 基金项目： | 国家自然科学基金
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| 摘 要： | 目的:比较灵芝孢子粉与子实体中三萜类化合物、多糖及重金属元素的含量差异。方法:采用高效液相色谱(HPLC)法分析灵芝孢子粉和子实体样品中的三萜类化合物,用电感耦合等离子体质谱(ICP-MS)技术对上述样品中5种重金属元素的含量进行测定,用蒽酮-硫酸法测定其中多糖的含量。结果:灵芝孢子粉和子实体中三萜类化合物的HPLC特征图谱差异明显;灵芝孢子粉中多糖的含量高于子实体中的含量;而重金属元素的含量二者没有显著差异。结论:本试验结果可为灵芝孢子粉与子实体药理作用的差异提供理论依据。
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| 关 键 词： | 灵芝孢子粉 灵芝子实体 三萜类化合物 多糖 重金属 含量 比较 |
Comparison of Contents of Triterpenoids, Polysaccharides and Heavy Metals in Ganoderma lucidum Sporule Powder and Ganoderma lucidum |
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| CHEN Jun-hui,WU Feng-qi,LI Wen-long,LI Xian-chun,WANG Xiao-ru,ZHANG Ding,HUANG Jian-yin.Comparison of Contents of Triterpenoids, Polysaccharides and Heavy Metals in Ganoderma lucidum Sporule Powder and Ganoderma lucidum[J].China Pharmacy,2008,19(33):2585-2587. |
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| Authors: | CHEN Jun-hui WU Feng-qi LI Wen-long LI Xian-chun WANG Xiao-ru ZHANG Ding HUANG Jian-yin |
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| Affiliation: | CHEN Jun-hui,CHEN Jun-hui, WU Feng-qi, LI Wen-long, LI Xian-chun, WANG Xiao-ru,ZHANG Ding, HUANG Jian-yin(College of Chemistry and Chemical Engineering, Ocean University of China, Qingdao 266003, China;Qingdao Key Lab on Analytical Technology Development and Standardization of Chinese Medicines, First Institute of Oceanography of State Oceanic Administration,Qingdao 266061,China; (Penta Biotech Inc, California 94587, USA) |
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| Abstract: | OBJECTIVE:To compare the contents of triterpenoids,polysaccharides and heavy metals in Ganoderma lucidum sporule powder and Ganoderma lucidum.METHODS:The triterpenoid compounds in Ganoderma lucidum sporule powder and Ganoderma lucidum samples were analyzed by HPLC;five heavy metals in the samples were determined by ICP-MS and the polysaccharides were quantified by anthrone-sulfuric acid method.RESULTS:There were significant differences beween Ganoderma lucidum sporule powder and Ganoderma lucidum in the HPLC characteristic chromatogram of triterpenoid compunds.The total content of polysaccharide in Ganoderma lucidum sporule powder was higher than in Ganoderma lucidum sample.However,the five heavy metals in the two materials showed no marked differences.CONCLUSION:This study provides theoretical basis for the pharmacological difference between Ganoderma lucidum sporule powder and Ganoderma lucidum. |
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| Keywords: | Ganoderma lucidum sporule powder Ganoderma lucidum Triterpenoid Polysaccharide Heavy metals Content Comparison |
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