慢肝汤联合复方甘草酸苷治疗慢性乙型肝炎的疗效观察

目的:观察慢肝汤联合复方甘草酸苷治疗慢性乙型肝炎的疗效。方法:将46例中度慢性乙型肝炎患者随机均分为治疗组和对照组,治疗组应用自拟慢肝汤治疗6mo,同时应用复方甘草酸苷治疗3mo;对照组应用甘草酸二铵、维生素、复方氨基酸注射液等常规治疗6mo。结果:治疗结束时治疗组肝功能及肝纤维化指标水平均显著好于对照组(P<0.05);治疗结束时治疗组HBV-DNA阴转10例,HBeAg阴转9例,ALT复常/HBV-DNA和HBeAg阴转9例,均显著好于对照组(P<0.05)。结论:慢肝汤联合复方甘草酸苷治疗慢性乙型肝炎有较好的疗效。

Clinical Therapeutic Observation of Man'gan Decoction Plus Compound Glycyrrhizin in the Treatment of Chronic Type B Hepatitis

OBJECTIVE:To observe the Therapeutic effect of Man'gan decoction plus compound glycyrrhizin in the trea_ tment of chronic type B hepatitis.METHODS:46patients with chronic hepatitis B were randomly divided into treatment group and control group.The treatment group was treated with self-planned Man'gan decoction for6mo plus compound glycyrrhizin for3mo;the control group received6months'conventional therapy-diammonium glycyrrhizinate,vitamin and amino acid compound injection,etc.RESULTS:At the end of treatment,the hepatic function and hepatic fibrosis index levels of the treatment group were superior to the control group(P<0.05)and in which group10cases whose HBV-DNA turned negative and9cases whose HBeAg turned negative;there were9cases whose ALT recovered to normal level and HBV-DNA and HBeAg turned negative in this group,which were also superior to the control group(P<0.05).CONCLUSION:The therapy of Man'gan decoction plus compound glycyrrhizin has a good therapeutic effect in the treatment of chronic type B hepatitis.