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234例药物不良反应分析
引用本文:徐颖颖,吕小琴,张相彩.234例药物不良反应分析[J].中国现代应用药学,2007,24(Z2).
作者姓名:徐颖颖  吕小琴  张相彩
作者单位:杭州市红十字会医院药剂科,杭州,310003
摘    要:目的分析我院药物不良反应(ADR)的发生情况及其给患者造成的伤害,为提高合理用药水平提供参考。方法对我院收集到的234例ADR病例报告进行分类统计和分析。结果抗微生物药物引起的ADR比例最高,位于前3位的是喹诺酮类、青霉素类和头孢菌素类;其次为循环系统药物。ADR以皮肤及附件损伤最常见,其次为消化系统损伤和输液样反应。结论应加强ADR监测及其相关知识的宣传,避免或减少其重复发生。

关 键 词:药物不良反应  用药监测  统计  合理用药

Analysisi on Monitoring Reports of 234 Cases of Adverse Drug Reactions in Our Hospital
XU Ying-ying,LV Xiao-qin,ZHANG Xiang-cai.Analysisi on Monitoring Reports of 234 Cases of Adverse Drug Reactions in Our Hospital[J].The Chinese Journal of Modern Applied Pharmacy,2007,24(Z2).
Authors:XU Ying-ying  LV Xiao-qin  ZHANG Xiang-cai
Abstract:OBJECTIVE To provide a rationale of safe pharmacotherapeutics by analyzing the incidence of adverse drug reactions(ADR).METHODS 234 incidences of ADR reported in the hospital were analyzed. RESULTS The highest incidence of ADR resulted from antibiotics,i.E.,quinolones,penicillins and cephalosporins.Other common ADRs were reported from circular system medicines.The most common ADRs occurred in the skin systems,and next in the digestive systems and infusion reaction.CONCLUSION To lessen or avoid the occurrence of ADRs,monitor and publicize of ADR knowledge should be emphasized.
Keywords:Adverse drug reaction  Monitoring of clinical drug  Statistics  Rational drug use
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