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1例新生儿耐碳青霉烯类肺炎克雷伯菌合并金黄色葡萄球菌感染的药学监护
引用本文:姚芳,张晓东,阿日贡高娃.1例新生儿耐碳青霉烯类肺炎克雷伯菌合并金黄色葡萄球菌感染的药学监护[J].中国药物应用与监测,2020(2):93-95.
作者姓名:姚芳  张晓东  阿日贡高娃
作者单位:内蒙古自治区妇幼保健院药剂科;内蒙古自治区药品检验研究院化妆品科;内蒙古自治区妇幼保健院新生儿科
基金项目:内蒙古自治区自然科学基金项目(2017MS0818)。
摘    要:1例新生儿因"早产儿、新生儿湿肺"收住入院。入院后气管插管末端细菌培养为耐碳青霉烯类肺炎克雷伯菌、脐静脉导管培养为敏感金黄色葡萄球菌,临床药师经分析建议分别给予氨曲南、头孢他啶抗感染治疗,经过积极治疗,患儿细菌培养结果呈阴性,感染指标下降,症状好转出院。临床药师在参与重点病例的治疗过程中,能有效协助医生解决治疗难点,提供药学角度的专业性建议,确保患儿治疗安全有效,体现了临床药师的专业价值。

关 键 词:耐碳青霉烯类肺炎克雷伯菌  金黄色葡萄球菌  新生儿  临床药师  药学监护

Pharmaceutical care on a case of a neonatal infection with carbapenem-resistant Klebsiella pneumoniae and Staphylococcus aureus
Affiliation:(Department of Pharmacy,Inner Mongolia MCH Hospital,Hohhot 010010,China;Department of Cosmetic,Inner Mongolia Drug Test Institute,Hohhot 010010,China;Department of Neonatal,Inner Mongolia MCH Hospital,Hohhot 010010,China)
Abstract:A neonate was admitted to the hospital due to premature and wet lung of newborn. After admission, culture of trachea cannula and umbilical vein catheterization showed carbapenem-resistant Klebsiella pneumoniae(CRKP) and sensitive Staphylococcus aureus respectively. Clinical pharmacist suggested giving aztreonam and ceftazidime after detailed analysis. After active treatment, results of bacterial cultures became negative and the infection indexes of the neonate decreased. It was discharged with the improved condition. During the course of the treatment for critical ill patient, clinical pharmacists could effectively help doctors to solve the therapeutic difficulties, provide rational therapeutic advice based on pharmacy, and ensure the safety and effectiveness of drug use, which reflected the professional value of the clinical pharmacists.
Keywords:Carbapenem-resistant Klebsiella pneumoniae  Staphylococcus aureus  Neonate  Clinical pharmacist  Pharmaceutical care
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