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对1例左胫腓骨骨折术后指甲隐球菌感染患者的药学监护
引用本文:邝俊健,吴丽明.对1例左胫腓骨骨折术后指甲隐球菌感染患者的药学监护[J].中国药物应用与监测,2011,8(1):32-34.
作者姓名:邝俊健  吴丽明
作者单位:广西梧州市中医院临床药学科,广西,梧州,543000
摘    要:1例47岁男性患者,左胫腓骨骨折术后伤口流脓并不愈合,经过脓液真菌培养及皮肤组织病理检查均找到指甲隐球菌,诊断为术后伤口组织真菌感染。临床药师参与治疗方案的评估,结合指甲隐球菌的病理结果,先后给予抗真菌药氟康唑和特比萘芬单独治疗,鉴于在用药过程中患者出现对氟康唑耐药以及特比萘芬致过敏性水疱等症状,立即调整用药方案,交替隔日使用2种抗真菌药物。患者接受抗真菌药物治疗1个多月后,症状得到较大改善。

关 键 词:氟康唑  特比萘芬  指甲隐球菌  临床药师  药学监护

Pharmaceutical care on a patient of nail cryptococcal infection with postoperative left tibiofibula fracture
Authors:KUANG Jun-jian  WU Li-ming
Affiliation:KUANG Jun-jian,WU Li-ming(Department of Clinical Pharmacy,Wuzhou Hospital of Traditional Chinese Medicine,Wuzhou 543000,China)
Abstract:One 47-year-old male patient with postoperative left tibiofibula fracture was hospitalized.According to the result of drug sensitive test and pathological test,the patient was diagnosed as nail cryptococcal infection with postoperative left tibiofibula fracture.Clinical pharmacists timely participated in the drug therapy combining with the pathological result of the nail cryptococcus.Fluconazole and terbinafine were selected as the anti-fungal treatment successively.For the patient appeared resistance to fl...
Keywords:Fluconazole  Terbinafine  Nail cryptococcus  Clinical pharmacist  Pharmaceutical care  
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