合理使用第三代头孢菌素类抗生素

目的：通过对第三代头孢菌素类抗生素的不良反应分析，为提高临床合理安全使用抗生素提供参考。方法采用回顾性调查方法，利用Excel对收集的不良反应报告进行统计，对不良反应的药品、给药途径、临床表现等数据分类统计和分析。结果第三代头孢菌素类抗生素不良反应涉及药品11种，涉及最多不良反应的是头孢曲松和头孢哌酮。药品不良反应累及7个器官或系统，比例最高的是变态反应。结论应关注头孢菌素类抗生素不良反应，提高合理用药水平。

Rational using of the third generation cephalosporins

Objective Through the analysis of adverse reactions to the third generation cephalosporin antibiotics, so as to provide reference for clinical rational use of antibiotics. Methods Using the method of retrospective investigation, and using Excellto collect adverse reaction reports and take statistics, to statistics and analysis the data of adverse reaction of drugs, routes of administration, clinical performance. Results The adverse reactions of the third generation of cephalosporin drugs related to 11 , involving the most adverse reaction of cefoperazone was rocephin and cefoperazone. Adverse drug reaction involved 7 organs or systems, and the highest proportion is allergic reaction. Conclusion We should pay attention to adverse reactions of cephalosporins to improve the level of rational use of drugs.