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| 电针刺激光明、外关组穴fMRI脑功能成像的研究 | |
| 引用本文： | 邱明国,王健,谢兵,巫北海,张绍祥,冯飞,米俊达,吴杰凤,黄艳萍.电针刺激光明、外关组穴fMRI脑功能成像的研究[J].第三军医大学学报,2005,27(19):1970-1972. |
| 作者姓名： | 邱明国 王健 谢兵 巫北海 张绍祥 冯飞 米俊达 吴杰凤 黄艳萍 |
| 作者单位： | 1. 第三军医大学西南医院放射科,重庆,400038;第三军医大学基础医学部解剖学教研室,重庆市计算医学研究所,重庆,400038 2. 第三军医大学西南医院放射科,重庆,400038 3. 第三军医大学基础医学部解剖学教研室,重庆市计算医学研究所,重庆,400038 4. 第三军医大学西南医院康复理疗科,重庆,400038 |
| 摘 要： | 目的建立脑功能磁共振成像(fMRI)技术平台,观察电针刺激光明(GB37)、外关(SJ5)组穴时对人脑功能的影响.方法选择5名健康志愿者,电针刺激光明(GB37)、外关(SJ5)组穴,采用Siemens公司Sonata 1.5T磁共振成像系统进行全脑功能扫描.数据经SPM软件统计分析得出刺激状态与静息状态信号对比的脑激活统计参数图,观察脑皮层相应功能区的激活状况.结果电针刺激右侧光明(GB37)及外关穴(SJ5)可使受试者双侧大脑枕叶距状沟附近的视觉皮质及顶下小叶皮层区的fMRI信号显著增加.结论特定的功能组穴与相应皮层兴奋区之间存在一定的相关性.fMRI影像技术结合SPM分析是研究电针作用机制的一种有效方法. |
| 关 键 词： | 功能磁共振成像 血氧水平依赖 统计参数图 电针 |
| 文章编号： | 1000-5404(2005)19-1970-03 |
| 收稿时间： | 2004-10-15 |
| 修稿时间： | 2005-01-18 |
Establishment of analyzing methods for functional MR images when electroacupuncture stimulation on Guangming and Waiguan acupoints |
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| QIU Ming-guo,WANG Jian,XIE Bing,WU Bei-hai,ZHANG Shao-xiang,FENG Fei,MI Jun-da,WU Jie-feng,HUANG Yan-ping.Establishment of analyzing methods for functional MR images when electroacupuncture stimulation on Guangming and Waiguan acupoints[J].Acta Academiae Medicinae Militaris Tertiae,2005,27(19):1970-1972. | |
| Authors: | QIU Ming-guo WANG Jian XIE Bing WU Bei-hai ZHANG Shao-xiang FENG Fei MI Jun-da WU Jie-feng HUANG Yan-ping |
| Affiliation: | 1 Department of Radiology, 3 Department of Rehabilitation and Physical Therapy, Southwest Hospital, 2 Department of Anatomy, College of Medicine, Third Military Medical University, Chongqing 400038, China |
| Abstract: | Objective To establish the analyzing methods for functional MR images, and investigate the effects of electroacupuncture stimulation to human brain function. Methods Electroacupuncture stimulation was performed at Guangming (GB37) and Waiguan (SJ5) acupoints in 5 healthy subjects, who had been scanned with Sonata 1.5T MRI (Siemens). Brain activity was measured with Statistical Parameter Mapping (SPM) software. Results Electroacupuncture stimulation of Guangming (GB37) and Waiguan (SJ5) acupoints produced prominent increases of fMRI signals in visual cortex and inferior parietal lobule. Conclusion Electroacupuncture stimulation of multiple acupoints can activate the specific areas of brain cortices. The fMRI technique and SPM analysis are powerful new tools to study the mechanism of electroacupuncture stimulation. |
| Keywords: | functional magnetic resonance imaging blood oxygenation level-dependent statistical parameter mapping electroacupuncture |
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