基于不同体重制定个性化造影剂方案对CT冠脉成像效果的影响

目的探究基于不同体重制定个性化造影剂方案对CT冠脉成像效果的影响。方法选取2017年4月至2018年5月我院心内科收治的102例疑似冠状动脉粥样硬化患者作为研究对象,按照随机数字法分为观察组和对照组,每组各51例。对照组采用传统注射方案,观察组根据患者体重采用个性化注射方案,两组均进行冠脉CT血管造影。观察并分析两组冠脉强化程度、CT冠脉成像质量、对比剂剂量及流速、安全性。结果观察组冠脉强化值明显高于对照组,差异具有统计学意义(P<0.05)。观察组CTA冠脉评分明显高于对照组,差异具有统计学意义(P<0.05)。观察组对比剂用量、流速明显低于对照组,差异具有统计学意义(P<0.05)。两组患者DLP(剂量长度乘积)、ED(有效辐射剂量)比较,差异无统计学意义(P>0.05)。结论基于不同体重制定个性化造影剂方案有利于降低CT冠脉成像对比剂剂量和流速,提高冠脉强化程度及效果。

Effect of Various Weight-Based Personalized Contrast Agent on CT Coronary Imaging

Objective To investigate the effect of various weight-based personalized contrast agents on CT coronary imaging.Methods A total of 102 patients with suspected coronary atherosclerosis admitted to our cardiology department from April 2017 to May 2018 were randomly divided into observation group(n=51,personalized injection protocol based on weight)and control group(n=51,traditional injection protocol).Both groups underwent coronary CT angiography.The degree of coronary artery enhancement,CT coronary angiography imaging quality,contrast dose,flow rate,and safety was observed and analyzed.Results The coronary enhancement value of the observation group was significantly higher than that of the control group(P<0.05).The CTA coronary score of the observation group was significantly higher than that of the control group(P<0.05).The contrast dose and flow rate in the observation group were significantly lower than those in the control group(P<0.05).There was no significant difference in DLP(dose length product)and ED(effective dose)between the two groups(P>0.05).Conclusion The development of various weight-based personalized contrast agent is beneficial to reduce the contrast dose and flow rate of CT coronary imaging and to improve the degree and effect of coronary artery enhancement.