猪脱细胞真皮与自体刃厚皮复合移植的临床应用

目的 观察深度烧伤和瘢痕切除创面进行猪脱细胞真皮与自体刃厚皮一步法与两步法复合移植的临床效果。方法 2000年4月-2002年12月间用猪脱细胞真皮与自体刃厚皮复合移植修复深度烧伤创面或瘢痕切除创面16例。对一步移植法和两步移植法进行比较。结果 一步移植法中，4例植皮完全成活，3例植皮95％以上成活，1例植皮80%成活；两步移植法中，5例植皮完全成活，3例植皮95％以上成活。均无l例补植皮。随访6个月-2年，一步和两步移植法中的复合移植皮肤外观、质地基本接近正常皮肤。瘢痕增生不明显。结论 猪脱细胞真皮与自体刃厚皮复合移植是深度烧伤创面、瘢痕切除创面的良好修复材料．一步移植法可行、简便、实用。

Clinical application of meshed porcine acellular dermis xenograft with split-thickness skin autograft]

OBJECTIVE: To observe the clinical effect of meshed porcine acellular dermis xenograft in conjunction with split- thickness skin autograft in the treatment of full-thickness skin burns and the wound after scar resection. METHOD: Sixteen patients receive the treatment with the skin grafts and the effects of one- and two-stage graftings were compared. RESULTS: In the patient group receiving one-stage grafting, 100% survival rate of the grafts was achieved in 4 cases, 95% in 3 cases, and 80% in 1 case. In two-stage grafting group, 100% survival rate of the grafts was achieved in 5 cases and more than 95% in 3 cases. No cases needed secondary grafting. During the follow-up of the patients for 6 months to 2 years, all the grafts assumed basically normal exterior appearance and texture without obvious scar formation. CONCLUSIONS: The combination of meshed porcine acellular dermis xenograft and split-thickness skin autograft was ideal for repairing full-thickness skin burns, for which one- stage grafting is both simple and practical.