腻滞质与正常质高血压前期人群动脉弹性功能的对照研究

目曲：探讨腻滞质与正常质高血压前期人群动脉弹性的变化情况。方珐：选择正常质、腻滞质理想血压健康者各30例；腻滞质高血压前期42例，正常质高血压前期36例；没有任何靶器官损害的1—2级腻滞质高血压患者38例，正常质高血压患者46例。使用CVProfilor DO-2020动脉弹性功能测定仪检测桡动脉脉搏波形和动脉弹性指数C1和C2，比较各组间大动脉、小动脉弹性及脉压差（PP）变化情况。结毒：各组间C1、C2、PP比较，校正了年龄和病程后，高血压组与高血压前期、理想血压组相比较，C1明显降低，有显著性差异（P〈0．05）；高血压前期腻滞质、高血压组与理想血压组、高血压前期正常质组相比较，C2明显降低，有显著性差异（P〈0．05）；高血压正常质与高血压前期腻滞质组比较，C2明显降低，有显著性差异（P〈0．05）；高血压腻滞质组与高血压正常质组C2比较，C2明显降低，有显著性差异（P〈0．05）。单因素相关分析结果显示：C1和C2与PP的相关性均较弱。结论；高血压前期患者已存在动脉弹性的减退；腻滞质可能是高血压病早期出现动脉弹性降低的重要因素。

Comparison of Arterial Elasticity Between Phlegm-Dampness Constitution and Normal Constitution Prehypertensive People

Objective: To investigate the arterial elasticity of prehypertensive people with phlegm-dampness constitution and normal constitution. Methods: We collected healthy ideal blood pressure people with normal or phlegm-dampness constitution, thirty people each, 42 prehypertensive cases with phlegm-dampness constitution, 36 prehypertensive ones with normal constitution, and 38 I-II phase hypertension patients of phlegm-dampness constitution without any target organs damage, 46 hypertensive cases with normal constitution. Pulse wave of arteria radialis and arterial elastic indexes C1, C2 were detected by CVProfilor D0-2020 arterial pulse contour instrument. Results: C1 decreased in hypertensive patients compared with the ideal blood pressure groups and prehypertensive groups after adjustments for ages and disease durations; C2 decreased in prehypertensive people of phlegm-damp constitution and hypertensive patients, compared with the ideal blood pressure groups and prehypertensive people of normal constitution,P < 0.05; C2 decreased in hypertensive patients of normal constitution, compared with prehypertensive people of phlegm-damp constitution,P < 0.05; C2 decreased in hypertensive patients of phlegm-damp constitution, compared with hypertensive patients of normal constitution,P < 0.05. There was no significant correlation between C1 and C2 in pulse pressure. Conclusions: Small arterial elastic index(C2) decreases in prehypertensive people; phlegm-damp constitution may play an important role in depressed arterial elasticity of early hypertension.