温肾助阳药治疗甲状腺机能低下阳虚兔模型的组织学和组织化学观察 |
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引用本文: | 罗灼玲,张立群,李文,张赛霞,徐应培,徐敏,张晓晖,欧明.温肾助阳药治疗甲状腺机能低下阳虚兔模型的组织学和组织化学观察[J].广州中医药大学学报,1992(1). |
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作者姓名: | 罗灼玲 张立群 李文 张赛霞 徐应培 徐敏 张晓晖 欧明 |
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摘 要: | 本实验采用甲状腺切除术遣成甲状腺机能低下(简称为甲低)阳虚兔模型,对该模型肝脏、胰腺、脾脏和胸腺等与物质、能量代谢或免疫功能关系密切的器官,进行组织形态学及组织化学观察。结果表明,甲状腺机能低下阳虚兔模型的上述器官,在形态结构上均有不同程度的病损改变;其肝细胞琥珀酸脱氢酶(SDH)等酶活性的变化不明显,而RNA含量较高。在施行甲状腺切除术后服用温肾助阳中药的实验兔,上述器官形态结构上的损害程度减轻,肝糖元含量则增高。提示温肾助阳药对甲低阳虚兔的组织器官有一定的保护作用。
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关 键 词: | 补阳药[剂]/药理学 甲状腺机能减退/中医药疗法 阳虚/中医药疗法 补阳药[剂]/治疗应用 甲状腺机能减退/病理学 阳虚/病理学 |
Histological and Histochemical Observation on the Rabbit Model with Hypothyroidism Treated with Herbs for warming and Tonifying Kidney-yang |
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Abstract: | Histomorphological and histochemical observation of liver, pancreas and thymus gland in the rabbit model with hypothyroidism was reported. Histopathological changes were found on the above-said organs but RNA content in liver increased. After being treated with the herbs for warming and tonifying and tonifying kidney-yang, morphological changes of the above-said organs lessened and hepatic glucogen content increased. These results suggest that herbs for warming and tonifying kidney-yang might have an effect in protecting the organs of the animal with yang deficiency. |
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Keywords: | YANG REINFORCING AGENTS/pharm YANG DEFICIENCY/TCM ther HYPOTHYROIDISM/TCM ther YANG DEFICIENCY/pathol YANG REINFORCING AGENTS/ther use HYPOTHYROID ISM/pathol |
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