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肺癌患者血清ProGRP、CA125、CYFRA21-1和TPS检测的临床意义
引用本文:马秀清,陈良安,李春笋,梁志欣,王平.肺癌患者血清ProGRP、CA125、CYFRA21-1和TPS检测的临床意义[J].军医进修学院学报,2009,30(3):329-330.
作者姓名:马秀清  陈良安  李春笋  梁志欣  王平
作者单位:解放军总医院,北京,100853
摘    要:目的:探讨血清肿瘤标志物ProGRP、CA125、CYFRA21-1和TPS在肺癌诊断中的价值。方法:回顾性分析180例患者的临床资料和肿瘤标志物水平,评价肿瘤标志物与肺癌的关系。结果:肺癌组患者ProGRP、CA125、CYFRA21-1和TPS阳性率明显高于肺部良性病变组,三项或四项联合检测敏感性和特异性明显优于单项检测。结论:ProGRP、CA125、CYFRA21-1和TPS中至少三项联合检测可提高肺癌诊断的敏感性和特异性。

关 键 词:ProGRP  CA125  CYFRA21-1  TPS  肺肿瘤

Clinical significance of ProGRP,CA125,CYFRA21-1 and TPS measurement in patients with lung cancer
MA Xiu-qing,CHEN Liang-an,LI Chun-sun,LIANG Zhi-xin,WANG Ping.Clinical significance of ProGRP,CA125,CYFRA21-1 and TPS measurement in patients with lung cancer[J].Academic Journal of Pla Postgraduate Medical School,2009,30(3):329-330.
Authors:MA Xiu-qing  CHEN Liang-an  LI Chun-sun  LIANG Zhi-xin  WANG Ping
Affiliation:Chinese PLA General Hospital;Beijing 100853;China
Abstract:Objective:To evaluate the clinical value of tumor markers of ProGRP,CA125,CYFRA21-1 and TPS in the diagnosis of lung cancer.Methods:The serum levels of tumor markers and clinical data of 180 patients were reviewed retrospectively.Results:The positive rates of ProGRP,CA125,CYFRA21-1 and TPS were higher in lung cancer group than those in benign lung diseases group respectively.The sensitivity was obviously higher by combined measurement of ProGRP,CA125,CYFRA21-1 and TPS than that only by one tumor marker assa...
Keywords:ProGRP  CA125  CYFRA21-1  TPS  lung neoplasms  
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