| 注射用盐酸吉西他滨的局部用药安全性评价 |
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| 引用本文： | 张丽,刘辰鹏,邝少轶.注射用盐酸吉西他滨的局部用药安全性评价[J].海南医学院学报,2011,17(5):589-591. |
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| 作者姓名： | 张丽 刘辰鹏 邝少轶 |
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| 作者单位： | 海南医学院药学院,海南,海口,571101 |
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| 基金项目： | 海南医学院科研基金资助学报项目 |
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| 摘 要： | 目的:通过对注射用盐酸吉西他滨的安全性试验研究,评价其用药的安全性.方法:分别进行豚鼠全身过敏性试验,家兔血管刺激性试验及溶血性试验,观察注射用盐酸吉西他滨是否可引起过敏和对血管的刺激性,是否具有溶血作用.结果:注射用盐酸吉西他滨给药后未出现过敏反应,静脉注射未见明显刺激性,亦未见溶血及凝集反应.结论:注射用盐酸吉西他...
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| 关 键 词： | 注射用盐酸吉西他滨 刺激性 过敏性 溶血性 |
Security assessment for local application of gemcitabine hydrochloride injection |
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| ZHANG Li,LIU Chen-peng,KUANG Shao-yi.Security assessment for local application of gemcitabine hydrochloride injection[J].Journal of Hainan Medical College,2011,17(5):589-591. |
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| Authors: | ZHANG Li LIU Chen-peng KUANG Shao-yi |
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| Affiliation: | ZHANG Li,LIU Chen-peng,KUANG Shao-yi |
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| Abstract: | Objective： To evaluate the safety of gemcitabine hydrochloride injection.Methods： Sensitivity test,blood vessel stimulation test and hemolysis test were conducted on guinea pig and rabbits to observe whether gemcitabine hydrochloride could induce hypersensitive response,irritative response,hemolutic reaction and agglutination or not.Results： Neither hypersensitive reaction in guinea pig nor hemolytic reaction or agglutination in rabbits was observed no matter gemcitabine hydrochloride was administrated by intramuscular injection.Conclusions： The results indicate that gemcitabine hydrochloride injection is safe. |
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| Keywords: | Gemcitabine hydrochloride for Injection Stimulation Allergic Hemolysis |
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