| 肿瘤接种前,后低电离辐射对肿瘤转移的影响 |
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| 引用本文： | 黄帼,魏道严.肿瘤接种前,后低电离辐射对肿瘤转移的影响[J].上海医学,1996,19(3):125-125. |
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| 作者姓名： | 黄帼 魏道严 |
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| 作者单位： | 安徽医科大学核医学教研室 |
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| 摘 要： | Ｃ５７ＢＬ小鼠接受２５、５０、７５、１００ｍＧｙＸ线单次全身照射后，小鼠肺转移疆节数明显低于对照组，其中以７５ｍＧｙ组最低，再将荷瘤小鼠进行７５ｍＧｙＸ线照射，受照组肺转移结节数仍低于对照组。与此同时发现，７５ｍＧｙ照射的小鼠免疫功能明显增强。上述结果提示：小剂量电离辐射对肿瘤转移有抑制作用，其可能机制是其免疫刺激效应。
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| 关 键 词： | 低电离辐射 肿瘤转移 免疫功能 |
EFFECTS OF LOW IONIZING RADIATION ON IMPLANTED TUMOR METASTASIS |
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| Huang Guo,Wei Dao-yan,Jing Ao-xing,Wang Si-yin.EFFECTS OF LOW IONIZING RADIATION ON IMPLANTED TUMOR METASTASIS[J].Shanghai Medical Journal,1996,19(3):125-125. |
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| Authors: | Huang Guo Wei Dao-yan Jing Ao-xing Wang Si-yin |
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| Abstract: | After irradiation with 25,50,75 or 100 mGy X-rays,lung metastatic nodules of C57 BL/Bmice were less than that of control group,and the metastatic nodules of group with 75 mGyirradiation was the least of all.We also found that the whole-body irradiation with 75mGyxrays to tumor-bearing mice caused a decrease in the number of lung metastatic nodules. Atthe same time,and 75mGy X-rays radiation may enhance mice immune function,These re-sults suggested that low dose irradiation may suppress tumor metastasis,and its possiblemechanism may be that the low dose radiation induces immunoenhancement. |
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| Keywords: | Low ionizing radiation Tumor metastasis Immnue function |
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