| 黄芩苷对小鼠急性肝损伤的保护作用 |
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| 引用本文： | 姜英子,金学军,崔兴日,尹明福,金将杰,金成赞,南极星.黄芩苷对小鼠急性肝损伤的保护作用[J].延边医学院学报,2003,26(4):255-257. |
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| 作者姓名： | 姜英子 金学军 崔兴日 尹明福 金将杰 金成赞 南极星 |
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| 作者单位： | [1]延边大学药学院，吉林延吉133000 [2]延边脑科医院，吉林延吉133000 [3]延边大学医学院研究生处，吉林延吉133000 |
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| 摘 要： | 目的 ]探讨黄芩苷对小鼠急性肝损伤的保护作用 .方法 ]采用D 氨基半乳糖及D 氨基半乳糖和内毒素合用建立小鼠急性肝损伤模型 ,测定小鼠血清中GOT ,GPT的含量 .结果 ]腹腔注射 2 0 0mg/kg或 50 0mg/kg黄芩苷可以明显降低因D 氨基半乳糖及D 氨基半乳糖和内毒素合用所致肝损伤小鼠血清中GOT及GPT含量的升高 .结论 ]黄芩苷对于受损的小鼠肝脏有一定的保护作用
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| 关 键 词： | 肝疾病 植物 药用 小鼠 |
| 文章编号： | 1000-1824(2003)04-0255-03 |
| 修稿时间： | 2003年9月8日 |
Protective effects of the baicalin for acute liver injury in mice |
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| JIANG Ying-zi ,JIN Xue-jun ,CUI Xing-ri ,YIN Ming-fu ,JIN Jiang-jie ,JIN Cheng-zan ,NAN Ji-xing.Protective effects of the baicalin for acute liver injury in mice[J].Journal of Medical Science Yanbian University,2003,26(4):255-257. |
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| Authors: | JIANG Ying-zi JIN Xue-jun CUI Xing-ri YIN Ming-fu JIN Jiang-jie JIN Cheng-zan NAN Ji-xing |
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| Affiliation: | JIANG Ying-zi 1,JIN Xue-jun 1,CUI Xing-ri 1,YIN Ming-fu 1,JIN Jiang-jie 2,JIN Cheng-zan 3,NAN Ji-xing 1 |
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| Abstract: | OBJECTIVETo study the effects of the bai ca lin for two models of acute hepatic injury in mice.METHODSTw o acute hepatic injury models induced by D galactosamine(D GalN) or D GalN and l ipopolysaccharide(LPS) in mice were used. The content of GOT, GPT in serum were measured as indexes.RESULTSIp 200 or 500mg/kg of the baica lin could diseased the content of GOT and GPT in serum in acute liver injury of mice.CONCLUSIONThe baicalin has some of protective effects f or liver injury in mice. |
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| Keywords: | liver diseases plants medicinal mice |
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