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带蒂筋膜脂肪瓣促进肌腱愈合防止肌腱粘连的实验研究
引用本文:左强,章征源,张桦.带蒂筋膜脂肪瓣促进肌腱愈合防止肌腱粘连的实验研究[J].江西医学院学报,2006,46(2):37-40.
作者姓名:左强  章征源  张桦
作者单位:[1]南昌大学医学院研究生部,南昌330006 [2]南昌大学第二附属医院骨科,南昌330006 [3]内蒙古医学院第三附属医院肿瘤科,内蒙古包头014010
摘    要:目的应用带蒂筋膜脂肪瓣覆盖修复的肌腱,探讨一种既能够促进愈合又能防止粘连的肌腱修复方法。方法选取SD大鼠18只,每只大鼠的右后肢跟腱为实验组(FW),左后肢为对照组(TS)。FW组以筋膜脂肪瓣翻转蒂部后包裹覆盖修复的肌腱;TS组仅对肌腱做显微缝合修复。分别在术后2、4、8周采取标本,傲大体观察、组织学切片检查和功能恢复实验,并进行评估、分级和统计(paired/matched t-test和wilcoxon rank sum test)。结果大体和组织学观察,2、4、8周FW组肌腱愈合更优,而粘连度却小于TS组(P〈0.05);功能恢复实验,FW组关节的活动度大于TS组,平均73.9%比62.5%。结论肌腱缝合术后,利用带蒂筋膜脂肪瓣包裹覆盖修复位点,有促进肌腱愈合,防止粘连的作用。

关 键 词:筋膜脂肪瓣  促进愈合  防止粘连  肌腱损伤  大鼠
文章编号:1000-2294(2006)02-0037-04
收稿时间:11 29 2005 12:00AM
修稿时间:2005年11月29

Fascial Fat Flap with Pedicle on Promoting Tendon Healing and Preventing Adhesion:an Experimental Study in Rats
ZUO Qiang,ZHANG Zheng-yuan,ZHANG Hua.Fascial Fat Flap with Pedicle on Promoting Tendon Healing and Preventing Adhesion:an Experimental Study in Rats[J].Acta Academiae Medicinae Jiangxi,2006,46(2):37-40.
Authors:ZUO Qiang  ZHANG Zheng-yuan  ZHANG Hua
Affiliation:1a. Department of Postgraduate ,Medical College ; 1b. Department of Orthopedics, the Second Affiliated Hospital, Nanchang University, Nanchang 330006 China; 2. Department of Oncology ,the Third Affiliated Hospital of Inner-mengolia Medical College ,Baotou 014010,China
Abstract:Objective To evaluate the application of fascial fat flap with pedicle to wrap repaired tendon and to study a way on promoting tendon healing and preventing adhesion.Methods Using 18 SD rats,every right hind limb of rats as experiment group(FW group),and left hind limb as control group(TS group).In FW group,repaired tendon was wrapped with fascial fat flap after flipping pedicle;only repairing injured tendon with micro-suture in TS group.After having made specimen,macroscopic observation,histological observation and functional recovery test were performed at 2,4 and 8 weeks for evaluating,classification and analysis.Results Macroscopic and histologic observation showed that healing was better and adhesions were less severe in FW group at 2,4 and 8 weeks;The FW group was superior to TS group on flexion with averaging 73.9% to 62.5%.Conclusion Applying fascial fat flap with pedicle to wrap repaired tendon is useful pedicle on promoting tendon healing and preventing adhesion after operation.
Keywords:fascial fat flap  promoting healing  preventing adhesion  tendon injuries  rat
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