| MicroRNA和肿瘤 |
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| 引用本文： | 曹长运.MicroRNA和肿瘤[J].中国医药导报,2012,9(14):12-14. |
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| 作者姓名： | 曹长运 |
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| 作者单位： | 哈尔滨医科大学附属第三医院胸外科,黑龙江哈尔滨,150081 |
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| 摘 要： | microRNA（miRNA）是近年来发现的一种大小21~25个碱基的、非蛋白编码单链小分子RNA,它主要通过与靶标基因3′UTR的完全或不完全配对,下调参与许多重要细胞活动（包括发育、增殖、分化、凋亡）基因的表达。近年来关于miRNA在肿瘤领域的研究一直比较热门,它的发现为肿瘤发病机制的研究提供了新的思路,为肿瘤诊断和治疗提供了新的策略,具有重要的实际意义。
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| 关 键 词： | microRNA 非编码RNA 肿瘤 |
MicroRNAs and tumor |
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| CAO Changyun.MicroRNAs and tumor[J].China Medical Herald,2012,9(14):12-14. |
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| Authors: | CAO Changyun |
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| Affiliation: | (proofreader) Department of Thoracic Surgery,the Third Affiliated Hospital of Harbin Medical University,Heilongjiang Province,Harbin 150081,China |
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| Abstract: | MicroRNAs(miRNAs) is a recently discovered non-protein coding single-stranded small molecular RNA with a size of about 21-25 bases,which participates many important cellular activities(including development,proliferation,differentiation,apoptosis) through the complete or incomplete pairing with the target gene 3’UTR.In recent years,studies on miRNA in the tumor area have been popular.The discovery of miRNA has provided a new approach for the study of tumor pathogenesis and provided a new strategy for tumor diagnosis and treatment,thereby of important practical significance. |
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| Keywords: | MicroRNAs Non-coding RNA Tumor |
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