| 蒙药二味杜仲汤对去卵巢大鼠骨代谢无机元素影响的实验研究 |
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| 引用本文： | 董重阳,刘岩,高小明,李紫慕,刘晋,常虹.蒙药二味杜仲汤对去卵巢大鼠骨代谢无机元素影响的实验研究[J].内蒙古医学院学报,2010(Z1):4-7. |
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| 作者姓名： | 董重阳 刘岩 高小明 李紫慕 刘晋 常虹 |
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| 作者单位： | 内蒙古医学院;内蒙古医学院附属医院中医科;内蒙古医学院中医学院; |
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| 基金项目： | 国家自然科学基金(30560165); 内蒙古自治区自然科学基金(2009MS1134) |
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| 摘 要： | 目的:从骨密度、骨生物力学及骨代谢无机元素方面探讨蒙药"二味杜仲汤"治疗绝经后骨质疏松症的机制。方法:取84只雌性SD大鼠随机分成假手术组、模型组、己烯雌酚组(西药对照)、骨疏康组(中药对照)、蒙药"二味杜仲汤"高、中、低剂量组7组,每组12只。采用经典造模后,饲养90d,灌胃饲养90d后,测定实验大鼠离体股骨骨密度、骨生物力学、骨代谢无机元素等指标。结果:与模型组比较,用药后,实验各组大鼠骨密度、骨生物力学性能、骨代谢无机元素含量显著升高(P<0.01)。结论:蒙药"二味杜仲汤"可提高去卵巢大鼠离体骨骨密度和骨组织生物力学性能;提高骨抵御外力冲击的能力,显著增加实验大鼠离体骨矿含量指标。
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| 关 键 词： | 蒙药二味杜仲汤 去卵巢大鼠 骨代谢无机元素 实验研究 |
LABORATORY STUDY OF EFFECTS OF ERWEIDUZHONGTANG CAPSULES ON INORGANIC ELEMENTS OF BONE METABOLISM OF POSTMENOPAUSAL OSTEOPOROSIS IN EXPERIMENTAL RAT |
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| DONG Chong-yang,LIU Yan,GAO Xiao-ming,et al..LABORATORY STUDY OF EFFECTS OF ERWEIDUZHONGTANG CAPSULES ON INORGANIC ELEMENTS OF BONE METABOLISM OF POSTMENOPAUSAL OSTEOPOROSIS IN EXPERIMENTAL RAT[J].Acta Academiae Medicinae Neimongol,2010(Z1):4-7. |
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| Authors: | DONG Chong-yang LIU Yan GAO Xiao-ming |
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| Affiliation: | DONG Chong-yang,LIU Yan,GAO Xiao-ming,et al. (Inner Mongolia Medical College,Hohhot 010059 China) |
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| Abstract: | Objective:By studying the effects of Erweiduzhongtang capsules on bone mineral density,bone biomechanics, inorganic elements of bone metabolism of ovx,we understand the mechanism of treatment to postmenopausal osteoporosis about Erweiduzhongtang.Method: 84 female SD rats were randomly divided into 7groups,sham operation group,model group,Diethylstilbestrol group(western medicine control),Gushukang group(Chinese control),Erweiduzhongtang capsules high,medium and low dose groups,each section 12.By classical m... |
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| Keywords: | Erweiduzhongtang ovariectomized osteoporosis model inorganic elements of bone metabolism experimental study |
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