乙型肝炎肝硬化失代偿期并自发性细菌性腹膜炎的相关危险因素研究

目的 研究乙型肝炎肝硬化失代偿期并自发性细菌性腹膜炎（SBP）的相关危险因素.方法 随机选取我院及宝安西乡人民医院收治的100例乙型肝炎肝硬化失代偿期患者进行回顾性分析,依其是否并发SBP分为两组各50例,对一般资料、实验室检查（腹水蛋白、ALB、TBIL等）、肝功能分级（Child-Pugh）等相关危险因素作单因素分析和Logistic回归分析.结果 SBP组较非SBP组的腹水蛋白、ALB显著降低,在门静脉内径、脾脏厚度、TBIL的比较上显著增高（P＜0.05）,且两组的消化道出血史、Child-Pugh分级的组间差异显著（P＜0.05）.结论 腹水蛋白、Child-Pugh分级、ALB、TBIL、门静脉内径、脾脏厚度以及既往有消化道出血史是乙型肝炎肝硬化失代偿期并发SBP的危险因素.

Study of risk factors for spontaneous bacterial peritonitis in hepatitis B virus related decompensated liver cirrhosis patients

Objective To explore and investigate the risk factors of SBP in hepatitis B virus related decompensated liver cirrhosis patients. Methods A total of 100 cirrhotic patients treated in Baoan Xixiang people＇s Hospital were divided into SBP group （n=50）and non-SBP group （n=50）.Retrospectively analyzed the clinical data of the patients included general conditions ,clinical symptoms（ALB,TBIL） by multiple factor logistic regression model and single factor analy- sis. Results Ascitic fluid protein and ALB of SBP group decreased more than those in non SBP group, and the portal vein, thickness of spleen,TBIL increased significantly（P〈0.05）.The difference of gastrointestinal bleeding history, Child-Pugh classification between two groups were significantly （P〈0.05）. Conclusion The incidences of SBP is relat- ed to aseitie fluid total protein, Child-Pugh grades, ALB, TBIL and other risk factors.