肺水通道蛋白的研究进展 |
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引用本文: | 刘毅,;史振伟.肺水通道蛋白的研究进展[J].医学综述,2014(24):4448-4450. |
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作者姓名: | 刘毅 ;史振伟 |
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作者单位: | [1]河北联合大学研究生学院,河北唐山063000; [2]煤炭总医院肾内科,北京100028 |
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摘 要: | 调节细胞膜的水渗透性是维持生命的基本要求,水通道蛋白是细胞膜上一组与水通透性有关的转运蛋白。目前研究表明,水通道蛋白表达或功能的改变,可以改变细胞膜转运水的速度。水通道蛋白的异常表达可能与临床上各种形式的水肿形成相关,通过改变体内水的平衡可达到治疗疾病的目的。水通道蛋白在维持肺脏的液体平衡中同样起重要的作用。
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关 键 词: | 水通道蛋白 跨膜转运 肺水肿 |
Research Progress of Aquaporin in Lung |
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Affiliation: | LIU Yi, SHI Zhen-wei( 1. Graduate School, Hebei United University, Tangshan 063000, China ; 2. Department of Nephrology , China Meitan General Hospital, Beijing 100028, China) |
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Abstract: | Adjusting the water permeability of the cell membrane is the basic requirements for life main- raining. Aquaporin is a group of transporters related to water permeability. Current studies show that, aquaporin expression or function changes can change the water transport speed. Aquaporin abnormal expression may be related to a variety of clinical forms of edema, and altering the water balance could achieve treatment of the diseases. Aquaporin also plays an important role in maintaining the balance of lung fluid. |
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Keywords: | Aquaproin Transmembrane transport Pulmonary edema |
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