合并前列腺炎的良性前列腺增生症的临床分析

目的：分析前列腺炎与前列腺增生症（BPH）的关系，探讨前列腺炎在BPH病程中可能起的作用。方法：对2003年7月至2009年2月间的466例良性BPH患者的资料进行回顾性分析。所收集临床资料包括年龄、病史、国际前列腺症状评分（IPSS）、生活质量评分（QOL）、前列腺体积、前列腺特异性抗原（PSA）相关值、最大尿流率（Qmax），及是否出现急性尿潴留和接受相关手术治疗。结果：合并前列腺炎的患者423例（90.77%，PS/BPH组），单纯BPH患者43例（9.23%，BPH组）。与BPH组比较，PS/BPH组患者病史延长，IPSS和QOL评分明显增加，前列腺体积和移行带体积显著增大，最大尿流率减小，发生急性尿潴留的概率增高，接受外科治疗的比例也较大。但是，年龄和PSA相关值（总PSA、游离PSA、游离与总PSA的比值、PSA的密度）2组之间差异无统计学意义。结论：前列腺炎可能是BPH的病因之一，同时炎症可能会加重BPH患者的下尿路症状，增加急性尿潴留和相关手术的风险

Clinical analysis of benign prostate hyperplasia with prostatitis

ObjectiveTo analyze the clinical features of benign prostate hyperplasia (BPH) with prostatitis and the role of prostatitis in progression of BPH. MethodsFrom July 2003 to Feb. 2009, 466 patients diagnosed BPH were enrolled in this study. Several items including age, history, IPSS, volume of prostate, prostatic special antigen (PSA) and related parameters, Qmax, acute urinary retention (AUR) and the way of treatment were analyzed.ResultsA total of 423 patients were diagnosed as BPH with prostatitis (90.77%, PS/BPH group), and 43 were BPH without prostatitis (9.23%, BPH group). Compared with the BPH group, patient’s history of the PS/BPH group was longer, IPSS/QOL was increased, the volume of total prostate and transitional zone were larger, maximum flow rate was decreased and risk of AUR was increased, and the proportion of BPH-related surgery was higher.There was no significant difference in patient’s age, tPSA, fPSA, f/tPSA, and PSAD between the 2 groups. ConclusionProstatitis may be one etiological factor for BPH. Patients with inflammation were more likely to progress clinically in terms of lower urinary tract symptoms (LUTS), acute urinary retention (AUR), or BPH-related surgery.